Results 231 to 240 of about 172,214 (308)

Exploring biologically-based complementary and alternative medicine use among Irish cancer survivors: findings from a national survey. [PDF]

Oncologist
Scannell C, Sullivan ES, Matvienko-Sikar K, Grimes DR, Power D, Ryan A.   +5 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Medicinal Plants for Acne Vulgaris: An Evidence-Based Review of Treatments Promoted by Social Media. [PDF]

J Cosmet Dermatol
Parvizi MM, Saki N, Rostami Ghotbabadi Z, Kamali M, Salmanpour N, Namazi M, Pasalar M.   +6 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A qualitative study of Yorùbá culture and the utilisation of modern dental services for oral health. [PDF]

BMC Health Serv Res
Folayan MO, Bernard OT, Oduwole E, Babalola ETO, Balogun BJ, Olojo FO, Adegbite NK, Ogunfolakan BA, Oyelakin JO, Adesida A, Akintayo AA, Okunmakinde O, Johnson AO, Akande ID, Fasiku G, Olowoniyi MJ, Titus OS.   +16 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Complementary and Alternative Therapy Use Among Cancer Patients in Qassim: Patterns, Predictors, and Patient Perspectives. [PDF]

Cancer Manag Res
Alshamsan B, Alharbi LA, Alshudukhi RI, Alaql FA, Alsweed R, Alodhaybi N.   +5 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Power of their stories: faces of kernicterus - experience and perception of caregivers and their children in Northern Nigeria. [PDF]

BMJ Paediatr Open
Farouk ZL, Slusher TM, Ali A, Abdulkadir I, Diala UM, Satrom KM, Hassan L, Abdullahi FL, Gurama K, Jibril YN, Shehu S, Kanhu PU, Toma BO, Usman NH, Remme L, Bode-Thomas F, Oguche S, Ogala WN, Bhutani VK.   +18 more
europepmc   +1 more source