Results 241 to 250 of about 172,214 (308)

Remedying problems with remedies

, 2017
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Phytotherapeutic, Homeopathic Interventions and Bee Products for Pediatric Infections: A Scoping Review. [PDF]

Nutrients
Bertoni C, Alberti I, Parri N, Agostoni CV, Bettocchi S, Zampogna S, Milani GP.   +6 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The stories of the ageing population in Luton, United Kingdom on their experience of periodontal diseases healthcare. [PDF]

Front Public Health
Velpula KP, Jacob E.
europepmc   +1 more source

Homeopathic remedies

Veterinary Record, 1991
openaire   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Community Knowledge, Risk Perception and Health-Seeking Behaviour Toward Rabies in Ghana: One Health Implications. [PDF]

Trop Med Infect Dis
Dwaah PK, Awua-Boateng NY, Squire SA, Osei E, Kando D, Dunu RE, Nartey D, Djang-Fordjour H, Edze P.   +8 more
europepmc   +1 more source

Exploring the Lived Experience of Acne in the United States and the United Kingdom: Social Media Analysis. [PDF]

JMIR Dermatol
S Barbieri J, Delore V, Vieillard I, Samson S, Puentes E, Malaab J, Sambrès M, Talmatkadi M, Schück S.   +8 more
europepmc   +1 more source