Results 241 to 250 of about 680,674 (310)

Financial Burden of Scarring Alopecia: Insights from the Cicatricial Alopecia Patient Assessment and Impact Report-Scarring Alopecia Foundation Survey Study on Economic and Psychosocial Impact. [PDF]

Skin Appendage Disord
Spindler A, Maas D, Zappi I, Brinks AL, Lawrence CN, Kearney CA, Pickford J, Jefferson IS, Shobajo M, Senna MM, Shapiro J, Lo Sicco KI.   +11 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Conflict of Laws: Application of Foreign Remedies [PDF]

, 1961

core   +1 more source

Botanical drug preparations for alleviating hair loss in menopausal women: a global ethnopharmacological mini-review. [PDF]

Front Pharmacol
Huang Z, Zhao WJ, Gao YJ, Huang ZR, Huang QR, Cai SZ, Bi MH.   +6 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Experiences and actions taken by women to address delayed conception in Delhi, India: A qualitative study. [PDF]

PLOS Glob Public Health
Adhikary P, Mburu G, Habib NA, Kabra R, Kiarie J, Dhabhai N, Mazumder S.   +6 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Exhaustion of Administrative Remedies [PDF]

, 1971

core   +1 more source

Stigma and illness management among podoconiosis patients in rural Ethiopia: an intersectional-hermeneutic study. [PDF]

Int J Equity Health
Ayele B, Tadele G, Engdawork K.
europepmc   +1 more source