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Rethinking remimazolam: reconciling regulatory positioning with clinical reality. [PDF]
BJA OpenWingert T, Sneyd JR.
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European Journal of Clinical Pharmacology, 2019
The aim of the present study was to evaluate the safety, pharmacokinetic (PK) and pharmacodynamic (PD) properties of remimazolam besylate following single ascending dose (SAD) and continuous infusion in healthy Chinese volunteers.This was a randomized phase I study conducted in two parts.
Yi-Min Cui, Xia Zhao
exaly +3 more sources
The aim of the present study was to evaluate the safety, pharmacokinetic (PK) and pharmacodynamic (PD) properties of remimazolam besylate following single ascending dose (SAD) and continuous infusion in healthy Chinese volunteers.This was a randomized phase I study conducted in two parts.
Yi-Min Cui, Xia Zhao
exaly +3 more sources
Surgery
Remimazolam besylate, despite being widely used in various clinical settings, lacks evidence in cardiac anesthesia. This trial compared its efficacy with propofol in elective cardiac surgery.A total of 320 adult patients undergoing elective cardiac surgery via cardiopulmonary bypass between December 2024 and March 2025 were randomized 1:1 to either ...
Jingjia Shen +7 more
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Remimazolam besylate, despite being widely used in various clinical settings, lacks evidence in cardiac anesthesia. This trial compared its efficacy with propofol in elective cardiac surgery.A total of 320 adult patients undergoing elective cardiac surgery via cardiopulmonary bypass between December 2024 and March 2025 were randomized 1:1 to either ...
Jingjia Shen +7 more
openaire +2 more sources
Irish Journal of Medical Science
Acute respiratory distress syndrome (ARDS) is a life-threatening condition characterized by disruption of the alveolar-capillary barrier, non-cardiogenic pulmonary edema, and severe hypoxemia. Its core pathophysiology involves uncontrolled systemic inflammation and oxidative stress injury.
Pengfei Pan
exaly +3 more sources
Acute respiratory distress syndrome (ARDS) is a life-threatening condition characterized by disruption of the alveolar-capillary barrier, non-cardiogenic pulmonary edema, and severe hypoxemia. Its core pathophysiology involves uncontrolled systemic inflammation and oxidative stress injury.
Pengfei Pan
exaly +3 more sources
Aesthetic Surgery Journal
Abstract Background Use of local anesthesia and conscious sedation with a combination of a sedative and anesthetic drug during a surgical procedure is an approach designed to avoid intubation, which produces fewer adverse events compared to general anesthesia.
Yunping, Huang +10 more
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Abstract Background Use of local anesthesia and conscious sedation with a combination of a sedative and anesthetic drug during a surgical procedure is an approach designed to avoid intubation, which produces fewer adverse events compared to general anesthesia.
Yunping, Huang +10 more
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METHOD FOR OBTAINING AMORPHOUS REMIMAZOLAM BESYLATE
2022SÁNCHEZ CASALS CARLES +2 more
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