Results 51 to 60 of about 1,790 (125)
, 2022 Study objective: The objective of the study was to evaluate the safety and efficacy of remimazolam besylate versus propofol injection in patients undergoing colonoscopy.Design: A multicenter, randomized, non-inferiority, single-blind, parallel-controlled
Zhigang Cheng (647368) +6 more
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Comparative observation of the effectiveness and safety of remimazolam besylate versus dexmedetomidine in gastrointestinal surgery in obese patients. [PDF]
World J Gastrointest SurgBACKGROUND Surgery for obese patients carries a higher risk of anesthesia complications compared with surgery for nonobese patients. Thus, a safe and effective anesthesia strategy is necessary to improve the medical experience of such patients and ensure their safety.
Deng YF, Jiang XR, Feng ZG.
europepmc +3 more sources
Remimazolam besylate; overview of a novel benzodiazepine for general anesthesia
Anaesthesia, Pain & Intensive Care, 2022 Remimazolam, a novel, ultra-short-acting intravenous anesthetics, belongs to the benzodiazepine class of drugs and was approved for as a general anesthetic. Its pharmacological action is similar to that of midazolam. However, the differences in the metabolic pathway and pharmacokinetic profiles of its metabolites contribute to the faster offset of the ...
openaire +1 more source
Remimazolam-induced intracellular calcium elevation.
, 2022 (A) An example of a typical remimazolam-induced intracellular calcium elevation time series in HUVECs. Approximately one min after the administration of 300 μM remimazolam, an increase in the fluorescence intensity of Fluo-4 was observed, indicating that
Soma Noguchi (12029730) +8 more
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Remimazolam: Non-Clinical and Clinical Profile of a New Sedative/Anesthetic Agent
Frontiers in Pharmacology, 2021 A program to identify novel intravenous sedatives with a short and predictable duration of action was initiated in the late 1990’s by Glaxo Wellcome. The program focussed on the identification of ester-based benzodiazepine derivatives that are rapidly ...
Gavin J. Kilpatrick
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BMC Anesthesiology, 2023 Background Although the operation time of hysteroscopy is short, the incidence of postoperative nausea and vomiting is high. The aim of this study was to compare the incidence of postoperative nausea and vomiting in hysteroscopy when remimazolam is ...
Xiaoqiang Zhang, Shuang Li, Jing Liu
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Remimazolam-induced intracellular calcium elevation in HEK293 cells.
, 2022 (A) Remimazolam at a concentration greater than or equal to 300 μM significantly induced the elevation of intracellular calcium in a dose-dependent manner in HEK293 cells. (n = 3–5, * p (TIF)
Soma Noguchi (12029730) +8 more
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Correction to: Efficacy and safety of remimazolam besylate versus propofol during hysteroscopy: single-centre randomized controlled trial. [PDF]
BMC Anesthesiol, 2021 Zhang X, Li S, Liu J.
europepmc +4 more sources
Remimazolam-induced intracellular calcium elevation in SHSY-5Y cells and HUVECs.
, 2022 (A) Remimazolam at a concentration greater than or equal to 300 μM significantly induced the elevation of intracellular calcium in a dose-dependent manner in SHSY-5Y cells (n = 3–7, * p < 0.05, compared to control, one-way ANOVA followed by Dunnett’s ...
Soma Noguchi (12029730) +8 more
core +1 more source