Results 131 to 140 of about 15,752 (298)

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

open access: yesChemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow   +2 more
wiley   +1 more source

I remember that... Reminiscence groups with people with dementia: A valuable site for practice learning [PDF]

open access: yes, 2006
This paper describes a small scale group project developing and delivering reminiscence work with people with dementia and undertaken by social work students as part of their practice learning experiences. The potential for enhancing the student learning
Parker, Jonathan
core  

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

open access: yesCytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli   +3 more
wiley   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

The Effect of Reminiscence Exercise Therapy and Nursing Resource Management on the Psychological Well-being of Elderly in Nursing Homes: A Multi-Perspective Study

open access: yesPublic Health of Indonesia
Background: The aging population in Indonesia continues to grow rapidly, with projections reaching 19.8% by 2045 according to Indonesia's Central Bureau of Statistics (2022).
Fery Agusman Motuho Mendrofa
doaj   +1 more source

The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 733-760, April 2025.
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray   +2 more
wiley   +1 more source

Case studies in SenseCam use for cognitive stimulation therapy in early-stage dementia. [PDF]

open access: yes, 2011
Estimates suggest that Ireland will have 50,000 people with dementia by 2016 and over 100,000 by 2036. Combined with European total costs are estimated in 2005 at €130 billion.
Irving, Kate   +2 more
core  

Creativity and its link to epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Chloride Intracellular Channel 2 Can Function as a Malignant Factor in Head and Neck Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The association of chloride intracellular channel 2 (CLIC2) with tumors has remained unclear. However, recently, CLIC2 was found to exhibit antitumor properties in some tumors. In this study, we aimed to evaluate the clinical relevance of CLIC2 expression in head and neck squamous cell carcinoma (HNSCC) to determine whether it ...
Yuki Hosokawa   +9 more
wiley   +1 more source

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