Results 211 to 220 of about 15,752 (298)

Impact of adalimumab treatment on impairment of non‐professional activities in psoriasis patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Psoriasis can result in reduced quality of life, work productivity loss, and a significant restriction in non‐professional activities. This study investigates the effects of long‐term treatment with adalimumab regarding work ability, non‐professional activities, and health‐related quality of life in a large real‐word ...
Georgios Kokolakis, Sandra Philipp, Thomas Mosch, Björn Fritz, Robert Sabat   +4 more
wiley   +1 more source

TANC1::HTRA1 fusion in schwannomas

Brain Pathology, EarlyView.
Ilay Caliskan, Kanish Mirchia, Walter Patrick Devine, Melike Pekmezci   +3 more
wiley   +1 more source

Kant's Dialectic of Enlightenment

European Journal of Philosophy, EarlyView.
Abstract Kant's moral thought emphasizes both our ability to make adequate, immediate moral judgment, as well as our deep‐seated forms of self‐entrapment. Strikingly, these forms of self‐entrapment are not simply the result of reason being overpowered by forces external to it, but arise out of reason itself, as pathological versions of otherwise ...
Laurenz Ramsauer
wiley   +1 more source

Zebrafish models of developmental epileptic encephalopathy accurately reflect clinical electrographic biomarkers

Epilepsia, EarlyView.
Abstract Objective Developmental epileptic encephalopathies (DEEs) are epilepsy conditions characterized by significant severity and treatment challenges. Spectral components of the encephalogram (EEG) may provide a valuable biomarker of epileptic severity.
Paige Whyte‐Fagundes, Joseane Righes Marafiga, Bingyao Zhu, Scott C. Baraban   +3 more
wiley   +1 more source

Self soothing by reviewing favorite memories: an exploration of mobile application prototypes, which facilitate positive wellbeing via reminiscing [PDF]

, 2013
Afghan, A., Ancient, Claire, Good, Alice, Postolache, G., Socianu, A.   +4 more
core  

Olig2‐specific loss‐of‐function Slc35a2 results in hypomyelination and spontaneous seizures

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development represent major causes of drug‐resistant epilepsy, with mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy recognized as a distinct pathological entity. Pathogenic X‐linked SLC35A2, encoding the uridine diphosphate–galactose transporter, has been implicated ...
Tiffany M. Bartel, Chaitali Ghosh, Kathryn Bisaha, Jean Khoury, Ashley Nemes‐Baran, Ingmar Blumcke, Imad Najm   +6 more
wiley   +1 more source

Do we agree on seizure reduction after vagus nerve stimulation? Interrater reliability of retrospective and prospective seizure frequency ratings from the CONNECTiVOS database

Epilepsia, EarlyView.
Abstract Objective Although vagus nerve stimulation (VNS) is a well‐established neuromodulation therapy for drug‐resistant epilepsy, treatment outcomes remain heterogeneous. One possible source of variability lies in differing interpretations of seizure frequency ratings (SFRs).
Thiemo F. Dinger, Karim Mithani, Hosni Abu Al‐Hasan, Leeor Yefet, Farbod Niazi, Hrishikesh Suresh, Simeon M. Wong, Venethia Danthine, Alexandre Berger, Ivanna Yau, Lyndsey McRae, James T. Rutka, Eisha A. Christian, Shelly Weiss, Lauren Sham, Elizabeth Donner, Vann Chau, Hanan Al‐Johani, Flavio Leao Lima, Arjun Chandran, Ramazan Jabbarli, Ulrich Sure, Aristides Hadjinicolaou, Philippe Major, Alexander G. Weil, Jignesh Tailor, Taylor J. Abel, Madison Remick, Emefa Akwayena, Dewi Schrader, Robert J. Bollo, Matthew D. Smyth, Diane Aum, Sean Lew, Shelly Wang, Toba Niazi, Jeffrey S. Raskin, Elysa Widjaja, Howard L. Weiner, Nisha Gadgil, Melissa A. LoPresti, Aria Fallah, Elizabeth Kerr, Puneet Jain, George M. Ibrahim   +44 more
wiley   +1 more source

TbTim20 facilitates protein import at a low membrane potential in trypanosomes lacking the mitochondrial genome

The FEBS Journal, EarlyView.
Protein import into mitochondria relies on TIM complexes and the membrane potential. Trypanosoma brucei has a unique TIM complex, and the role of one subunit, TbTim20, has remained unclear. Here, we show that TbTim20 is essential in cells lacking mitochondrial DNA. The importance of TbTim20 increases as the membrane potential decreases.
Corinne von Känel, Salome Aeschlimann, Michaela Husová, Silke Oeljeklaus, Philip Stettler, Achim Schnaufer, Bettina Warscheid, Alena Zíková, André Schneider   +8 more
wiley   +1 more source