Results 41 to 50 of about 89,423 (306)

A Case of Statin-Associated Autoimmune Myopathy. [PDF]

, 2017
A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N, Farjami, Sassan, Kaiser, Cassandra J, Leung, Anthony, Romansky, Stephen, Strube, Sarah J, Sweidan, Alexander J   +6 more
core   +3 more sources

The development remission of acromegaly in the outcome of intraoperative bleeding in somatoprolactinomas

Эндокринная хирургия, 2012
In this article we describe a rare case of spontaneous remission of acromegaly as a consequence of hemorrhage to pituitary adenoma and subarachnoid space, followed after intraoperative bleeding during transnasal removal of somatoprolactinomas.
A Y Grigorev, V N Azizyan, O V Ivashchenko, N N Molitvoslovova   +3 more
doaj   +1 more source

Hierarchy in Gene Expression is Predictive for Adult Acute Myeloid Leukemia

, 2015
Cancer progresses with a change in the structure of the gene network in normal cells. We define a measure of organizational hierarchy in gene networks of affected cells in adult acute myeloid leukemia (AML) patients.
Deem, Michael W., Tripathi, Shubham
core   +1 more source

Tumor-associated and immunochemotherapy-dependent long-term alterations of the peripheral blood NK cell compartment in DLBCL patients [PDF]

, 2015
Natural Killer (NK) cells are a key component of tumor immunosurveillance and thus play an important role in rituximab-dependent killing of lymphoma cells via an antibody-dependent cellular cytotoxicity (ADCC) mechanism.
Battella, Simone, Cecere, Francesca, DI NAPOLI, Arianna, Eleonora, Alma, LA SCALEIA, Raffaella, M., Christina Cox, Mainiero, Fabrizio, Monarca, Bruno, Palmieri, Gabriella, Pelliccia, Sabrina, Porzia, Alessandra, Ruco, Luigi, Santoni, Angela, Zingoni, Alessandra   +13 more
core   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Intraoperation haemorrhage into hypophysis adenoma as the cause of acromegaly remission

Эндокринная хирургия, 2011
In this article we describe a spontaneous remission of acromegaly of intraoperative bleeding, with subsequent hemorrhage into the tumor. The cases of spontaneous remission of acromegaly described in the literature have been associated mainly with ...
V N Azizyan, A U Grigorjev, O V Ivaschenko, N N Molitvoslovova   +3 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Problematic technology use during adolescence: why don’t teenagers seek treatment? [PDF]

, 2015
In recent issues of Education and Health, I have briefly reviewed the empirical evidence relating to problematic use of technology by adolescents including online video gaming (Griffiths, 2014), social networking (Griffiths, 2013a; Kuss & Griffiths, 2011)
Griffiths, MD
core  

What's in a Name? Classification of Diabetes Mellitus in Veterinary Medicine and Why It Matters [PDF]

, 2016
Diabetes Mellitus (DM) is a syndrome caused by various etiologies. The clinical manifestations of DM are not indicative of the cause of the disease, but might be indicative of the stage and severity of the disease process.
Abdul-Rasoul, Agarwal, Ahlgren, Alejandro, American Diabetes Association, Anderson, Appleton, Atkins, Atkins, Batchelor, Belle, Bostrom, Brackeva, Brenner, Butler, Catchpole, Catchpole, Chiang, Concannon, Coppieters, Cui, Das, Davison, Davison, Davison, De Cock, Eigenmann, Fajans, Fall, Forcada, Forcada, Forsberg, Furrer, Gepts, Gilor, Gilor, Gilor, Girman, Goossens, Gostelow, Gottlieb, Guptill, Haines, Hall, Herold, Hess, Hewson-Hughes, Hoenig, Hoenig, Hoffmann, Holst, Hume, Imamura, Jensen, Kappe, Kennedy, Kenny, Kilpatrick, Kim, Kitamura, Klupa, Kramer, Kramer, Lem, Ling, Link, Lutz, Mattin, McDonald, Miceli, Michels, Neiger, Nelson, Nelson, Niessen, Niessen, Nishii, Orban, Panciera, Papa, Pietropaolo, Porte, Porte, Prahl, Prasad, Rand, Ranta, Reaven, Russell-Jones, Safra, Scudder, Shields, Slingerland, Solanki, Strage, Sun, Temple, Thomas, Vegiopoulos, Verkest, Watson, Watson, Williams, Xenoulis, Yang, Zini, Zini, Zini, Zini, Zini, Zini   +110 more
core   +3 more sources

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source