Results 51 to 60 of about 89,423 (306)

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source

Microstructure‐Resolved Modeling to Predicting and Regulating Lithium Plating‐Stripping Dynamics on Graphite Electrodes

Advanced Science, EarlyView.
ABSTRACT The lithium plating reaction in graphite electrodes acts as a root cause for the accelerated degradation and the internal short circuits in lithium‐ion batteries. Here, an electrochemical model based on multi‐scale microstructural images was established to identify lithium plating‐stripping processes, thereby supporting the predictive outcomes
Heng Huang, Yang Li, Xinyu Liu, Zhifu Zhou, Wei‐Tao Wu, Lei Wei, Chengzhi Hu, Linsong Gao, Yubai Li, Yongchen Song   +9 more
wiley   +1 more source

Long‐term outcome of cats with acquired myasthenia gravis without evidence of a cranial mediastinal mass

Journal of Veterinary Internal Medicine, 2020
Background Acquired myasthenia gravis (AMG) is increasingly recognized in cats, yet information regarding the natural history of the disease, treatment, and outcome including occurrence of immune and spontaneous remission remains limited.
Thomas Mignan, Laurent Garosi, Mike Targett, Mark Lowrie   +3 more
doaj   +1 more source

Spontaneous Remission in a Patient with Chronic Myeloid Leukemia: A Case Report

Case Reports in Oncology, 2023
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm in which granulocytic cells are the main proliferative component. At diagnosis, more than 90% of CML cases have the characteristic Philadelphia chromosome, containing the BCR::ABL1 fusion ...
Awni Alshurafa, Yeslem Ekeibed, Susanna Akiki, Muna Alzeyara, Zafar Nawaz, Mohamed A. Yassin   +5 more
doaj   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Analysis of primary treatment and prognosis of spontaneous urticaria

Allergology International, 2017
Background: The prognosis of spontaneous urticaria in association with early treatment remains unclear. In this study, we retrospectively studied the prognosis of acute spontaneous urticaria in relation to age and treatments in a local clinic of ...
Toshihiko Tanaka, Makiko Hiragun, Michihiro Hide, Takaaki Hiragun   +3 more
doaj   +1 more source

NELL1-Positive HIV-Associated Lupus-Like Membranous Nephropathy with Spontaneous Remission

Glomerular Diseases, 2022
Introduction: Kidney biopsy findings in patients with human immunodeficiency virus (HIV) are diverse, and optimal therapy for the various immune complex diseases in the setting of HIV is unknown.
Kumar P. Dinesh, Vivek Charu, Megan L. Troxell, Nicole K. Andeen   +3 more
doaj   +1 more source

Pediatric liver diseases: current challenges and future perspectives [PDF]

, 2015
Chronic liver diseases in children represent a rising problem with significant effects on public health. In fact, several pediatric liver diseases are precursors of adult chronic hepatopathies, cirrhosis and hepatocellular carcinoma.
Alisi, Anna, Alterio, Arianna, Della Corte, Claudia, Mosca, Antonella, Nobili, Valerio, Vania, Andrea   +5 more
core   +1 more source

Collaborating with transnational families: Learning from the experiences of family caretakers, educators, psychologists, and spiritual leaders in Honduras

American Journal of Community Psychology, EarlyView.
Abstract This manuscript centers on the experiences of caretakers of minors in Honduran transnational families (TNFs) in which one or both parents emigrated, and of the schoolteachers, professional psychologists, and spiritual leaders working with these families.
Marco Gemignani, Yolanda Hernández‐Albújar, Nerea Larrinaga‐Bidegain   +2 more
wiley   +1 more source

Spontaneous resolution of acute gout: mechanisms and therapeutic targets

RMD Open, 2023
Gout is a common inflammatory arthritis that has been increasing in both prevalence and incidence. Consequently, management of refractory and chronic gout has been gaining attention. Onset of gout is related to the deposition of monosodium urate crystals
Meiling Shi, Jiao Luo, Liting Ding, Lihua Duan   +3 more
doaj   +1 more source