Results 71 to 80 of about 90,197 (309)

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Bath-Related Headache [PDF]

, 2018
PURPOSE OF REVIEW: The purpose of this review is to summarize the most up-to-date literature on bath-related headache, a rare disorder. RECENT FINDINGS: Initially described in middle-aged Asian women, it is now reported in a wider demographic.
Kumpinsky, Aliza, Nahas, Stephanie J.
core   +1 more source

Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) model. [PDF]

, 2016
A patient with high grade undifferentiated pleomorphic soft-tissue sarcoma from a striated muscle was grown orthotopically in the right biceps femoris muscle of mice to establish a patient-derived orthotopic xenograft (PDOX) model.
Bouvet, Michael, Chawla, Sant, Chishima, Takashi, DeLong, Jonathan, Deng, Samantha, Eilber, Fritz C, Endo, Itaru, Hiroshima, Yukihiko, Hoffman, Robert M, Matsuyama, Ryusei, Murakami, Takashi, Quan, Cuong, Reynoso, Jose, Russell, Tara, Singh, Arun, Tanaka, Kuniya, Zhang, Nan, Zhang, Yong, Zhao, Ming   +18 more
core   +3 more sources

T‐prolymphocytic leukaemia with spontaneous remission [PDF]

British Journal of Haematology, 2000
T‐prolymphocytic leukaemia (T‐PLL) is a rare dis‐order with a poor prognosis. A 69‐year‐old man was diagnosed as having a small‐cell variant of T‐PLL according to the French–American–British classification by haematological, immunological and ultrastructural studies, although the cells had a CD7− phenotype and no chromosomal abnormality.
T, Shichishima, M, Kawaguchi, T, MacHii, R, Matsuoka, K, Ogawa, Y, Maruyama   +5 more
openaire   +2 more sources

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Predictors of spontaneous remission in school students with Internet use disorders: Systematic review and meta-analysis

Консультативная психология и психотерапия
Context and relevance. Internet use disorders (IUDs), which include different types of behavioral addiction patterns related to inappropriate or excessive internet use, have become a major problem among children and adolescents.
Y.V. Malygin, L.S. Zolotareva, A.S. Orlova, O.A. Mokienko, V.L. Malygin   +4 more
doaj   +1 more source

Role of antiviral therapy in the natural history of hepatitis B virus-related chronic liver disease [PDF]

, 2015
Hepatitis B virus (HBV) infection is a dynamic state of interactions among HBV, hepatocytes, and the host immune system. Natural history studies of chronic hepatitis B (CHB) infection have shown an association between active viral replication and adverse
Farinati, Fabio, Gottardo, G, Rodr\uedguez Castro, K, Russo, FRANCESCO PAOLO, Scribano, L, Vanin, V   +5 more
core   +1 more source

Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases

Advanced Science, EarlyView.
Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh, Amir Tahavvori, Cyrus E. Kuschner, Blanca B. Espin, Jacob Kazmi, Sofhia V. Ramos, Tai Yin, Kei Hayashida, Kanako Ito‐Hagiwara, Yusuke Endo, Keitaro Yoshioka, Jun Hagiwara, Avijot Sohi, Alisha Oropallo, Ghania Haddad, Timmy Li, Lance B. Becker, Junhwan Kim   +17 more
wiley   +1 more source

Collaborating with transnational families: Learning from the experiences of family caretakers, educators, psychologists, and spiritual leaders in Honduras

American Journal of Community Psychology, EarlyView.
Abstract This manuscript centers on the experiences of caretakers of minors in Honduran transnational families (TNFs) in which one or both parents emigrated, and of the schoolteachers, professional psychologists, and spiritual leaders working with these families.
Marco Gemignani, Yolanda Hernández‐Albújar, Nerea Larrinaga‐Bidegain   +2 more
wiley   +1 more source

Spontaneous complete remission of type 1 diabetes mellitus in an adult – review and case report [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2015
Type 1 diabetes mellitus (T1DM) is an autoimmune condition that results in low plasma insulin levels by destruction of beta cells of the pancreas. As part of the natural progression of this disease, some patients regain beta cell activity transiently ...
Harsha Moole, Vishnu Moole, Adrija Mamidipalli, Sowmya Dharmapuri, Raghuveer Boddireddy, Deepak Taneja, Hady Sfeir, Sonia Gajula   +7 more
doaj   +1 more source