Biomedicines, 2022 A type 2 diabetes mellitus (T2DM) subtyping method that determines the T2DM phenotype based on an extended oral glucose tolerance test is proposed. It assigns participants to one of seven subtypes according to their β-cell function and the presence of ...
Iris M. de Hoogh +4 more
doaj +1 more source
Predictors and outcomes of sustained, intermittent or never achieving remission in patients with recent onset inflammatory polyarthritis:Results from the Norfolk Arthritis Register [PDF]
, 2016 Objectives: Early remission is the current treatment strategy for patients with inflammatory polyarthritis (IP) and RA. Our objective was to identify baseline factors associated with achieving remission: sustained (SR), intermittent (IR) or never (NR ...
Cook, Michael J +6 more
core +1 more source
The Big Pet Diabetes Survey: Perceived Frequency and Triggers for Euthanasia
Veterinary Sciences, 2017 Current pet diabetes mellitus (DM) treatment necessitates the active daily involvement of owners and can be costly. The current study aimed to investigate the owner population which opts for euthanasia instead of DM treatment. A survey was designed using
Stijn J.M. Niessen +7 more
doaj +1 more source
Cognitive Impairment and Neurocognitive Profiles in Major Depression—A Clinical Perspective
Frontiers in Psychiatry, 2022 Increasingly, studies have investigated cognitive functioning from the perspective of acute state- to remitted phases of Major Depressive Disorder (MDD).
Åsa Hammar +4 more
doaj +1 more source
The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]
, 2010 Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y. +2 more
core +1 more source
Pasireotide Long‐Acting Release Treatment for Diabetic Cats with Underlying Hypersomatotropism
Journal of Veterinary Internal Medicine, 2017 Background Long‐term medical management of hypersomatotropism (HS) in cats has proved unrewarding. Pasireotide, a novel somatostatin analogue, decreases serum insulin‐like growth factor 1 (IGF‐1) and improves insulin sensitivity in cats with HS when ...
R. Gostelow +7 more
doaj +1 more source
The Diabetes Remission Clinical Trial (DiRECT): protocol for a cluster randomised trial [PDF]
, 2016 Background: Despite improving evidence-based practice following clinical guidelines to optimise drug therapy, Type 2 diabetes (T2DM) still exerts a devastating toll from vascular complications and premature death.
Adamson, Ashley +19 more
core +3 more sources
Radio-chemotherapy as a preoperative treatment for advanced rectal cancer. Evaluation of down-staging and morbidity [PDF]
, 2002 Background: The standard therapy for patients with clinically resectable rectal cancer is generally considered to be surgery, If the patient is diagnosed with advanced disease, postoperative radiochemotherapy (RCT) is usually recommended. In our study we
Dühmke, Eckhart +4 more
core +1 more source
The analysis of treatment of Immunoglobulin A-nephropathy [PDF]
Терапевтический архив, 2020 Aim. An evaluation of the effectiveness of immunosuppressive therapy (IST) and tonsillectomy (TE) in patients with IgA nephropathy (IgAN). Materials and methods. A retrospective cohort of the study included cases with biopsy proven primary IgAN (n=367,
Vladimir A. Dobronravov +3 more
doaj +1 more source
Dual antibody status predicts sustained remission in patients with rheumatoid arthritis
Indian Journal of Rheumatology, 2019 Background: Rheumatoid factor (RF) and anti-cyclic citrullinated protein (ACCP) estimation have been used to improve the diagnosis of rheumatoid arthritis (RA).
Praveen Pratap Jadhav +6 more
doaj +1 more source