Results 21 to 30 of about 922,637 (337)

Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial.

The Lancet Diabetes and Endocrinology, 2019
BACKGROUND The DiRECT trial assessed remission of type 2 diabetes during a primary care-led weight-management programme. At 1 year, 68 (46%) of 149 intervention participants were in remission and 36 (24%) had achieved at least 15 kg weight loss.
M. Lean, W. Leslie, A. Barnes, Naomi Brosnahan, G. Thom, Louise McCombie, C. Peters, S. Zhyzhneuskaya, A. Al-Mrabeh, K. Hollingsworth, Angela M Rodrigues, L. Rehackova, A. Adamson, F. Sniehotta, J. Mathers, H. Ross, Yvonne McIlvenna, P. Welsh, S. Kean, I. Ford, A. McConnachie, C. Messow, N. Sattar, Roy Taylor   +23 more
semanticscholar   +1 more source

The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas [PDF]

, 2010
Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent ...
Liu, Charles Y., Stapleton, Christopher J., Weiss, Martin H.   +2 more
core   +1 more source

Pasireotide Long‐Acting Release Treatment for Diabetic Cats with Underlying Hypersomatotropism

Journal of Veterinary Internal Medicine, 2017
Background Long‐term medical management of hypersomatotropism (HS) in cats has proved unrewarding. Pasireotide, a novel somatostatin analogue, decreases serum insulin‐like growth factor 1 (IGF‐1) and improves insulin sensitivity in cats with HS when ...
R. Gostelow, C. Scudder, S. Keyte, Y. Forcada, R.C. Fowkes, H.A. Schmid, D.B. Church, S.J.M. Niessen   +7 more
doaj   +1 more source

Crohn's Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial.

Gastroenterology, 2019
BACKGROUND & AIMS Exclusive enteral nutrition (EEN) is recommended for children with mild-to-moderate Crohn's disease (CD) but implementation is challenging.
A. Levine, E. Wine, A. Assa, R. Sigall Boneh, R. Shaoul, M. Kori, Shlomi Cohen, S. Peleg, H. Shamaly, A. On, P. Millman, L. Abramas, T. Ziv-Baran, S. Grant, G. Abitbol, K. Dunn, J. Bielawski, J. V. van Limbergen   +17 more
semanticscholar   +1 more source

Combination of transsphenoidal endoscopic surgery and presurgical somatostatin analogs in thyrotropin (TSH)-secreting pituitary adenomas: Treatment outcome and long-term remission at a single pituitary center

Frontiers in Endocrinology, 2022
BackgroundThyrotropin (TSH)-secreting pituitary adenomas (TSHomas) account for an extremely rare group of pituitary adenomas. Few studies examined the sensitivity and efficacy of presurgical somatostatin analogs (SSAs) and described the long-term ...
Jie Liu, Yamei Yang, Yamei Yang, Lian Duan, Lian Duan, Xiaofeng Chai, Xiaofeng Chai, Huijuan Zhu, Huijuan Zhu, Kan Deng, Xiaolan Lian, Xiaolan Lian, Yong Yao   +12 more
doaj   +1 more source

Oral Azacitidine Maintenance Therapy for Acute Myeloid Leukemia in First Remission.

New England Journal of Medicine, 2020
BACKGROUND Although induction chemotherapy results in remission in many older patients with acute myeloid leukemia (AML), relapse is common and overall survival is poor. METHODS We conducted a phase 3, randomized, double-blind, placebo-controlled trial
A. Wei, H. Döhner, C. Pocock, P. Montesinos, B. Afanasyev, H. Dombret, F. Ravandi, H. Sayar, J. Jang, K. Porkka, D. Selleslag, I. Sandhu, M. Turgut, Valentina Giai, Y. Ofran, M. Kızıl Çakar, A. Botelho de Sousa, J. Rybka, C. Frairia, L. Borin, G. Beltrami, J. Čermák, G. Ossenkoppele, I. La Torre, B. Skikne, Keshava Kumar, Qian Dong, C. Beach, G. Roboz   +28 more
semanticscholar   +1 more source

Helicobacter pylori Eradication Therapy Is Effective as the Initial Treatment for Patients with H. pylori-Negative and Disseminated Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

Gut and Liver, 2016
Background/AimsWe investigated the effectiveness of Helicobacter pylori eradication therapy for gastric mucosa-associated lymphoid tissue (MALT) lymphoma regardless of the H.
Eun Jeong Gong, Ji Yong Ahn, Hwoon-Yong Jung, Hyungchul Park, Young Bo Ko, Hee Kyong Na, Kee Wook Jung, Do Hoon Kim, Jeong Hoon Lee, Kee Don Choi, Ho June Song, Gin Hyug Lee, Jin-Ho Kim   +12 more
doaj   +1 more source

Detection of monosomy 7 in interphase cells of patients with myeloid disorders [PDF]

, 1990
Six patients, five with acute myeloid leukemia (AML) and one with a myelodysplastic syndrome (MDS), were found to have monosomy 7 by conventional cytogenetics at diagnosis.
Cremer, Thomas, Gezer, Sefer, Kolluri, Rukmini V., Manuelidis, L., Raza, Azra, Sait, Sheila   +5 more
core   +1 more source

Effect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis: A Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2019
Importance High-intensity, aerobically prepared fecal microbiota transplantation (FMT) has demonstrated efficacy in treating active ulcerative colitis (UC).
S. Costello, P. Hughes, O. Waters, R. Bryant, A. Vincent, P. Blatchford, R. Katsikeros, J. Makanyanga, Melissa A. Campaniello, C. Mavrangelos, C. Rosewarne, C. Bickley, C. Peters, M. Schoeman, M. Conlon, I. Roberts-Thomson, J. Andrews   +16 more
semanticscholar   +1 more source

Fecal microbiota transplantation to maintain remission in Crohn’s disease: a pilot randomized controlled study

Microbiome, 2020
The role of the gut microbiota in Crohn’s disease (CD) is established and fecal microbiota transplantation (FMT) is an attractive therapeutic strategy. No randomized controlled clinical trial results are available. We performed a randomized, single-blind,
Harry Sokol, C. Landman, P. Seksik, L. Berard, M. Montil, I. Nion‐Larmurier, A. Bourrier, G. Le Gall, V. Lalande, A. de Rougemont, J. Kirchgesner, A. Daguenel, M. Cachanado, A. Rousseau, E. Drouet, M. Rosenzwajg, H. Hagège, Xavier Dray, D. Klatzman, P. Marteau, Lionel Laurent Anne Marine Najim Édouard Ulriikka Chloé L Arrivé Beaugerie Bourrier Camus Chafai Chambenois , L. Arrivé, Laurent Beaugerie, A. Bourrier, M. Camus, N. Chafai, E. Chambenois, U. Chaput, C. Martineau, L. Monnier-Cholley, C. Debove, Xavier Dray, J. Fléjou, Nadia Hoyeau, J. Kirchgesner, C. Landman, J. Lefèvre, P. Marteau, I. Nion‐Larmurier, V. Ozenne, Y. Parc, P. Seksik, Harry Sokol, M. Svrcek, Laurent Beaugerie, T. Simon   +45 more
semanticscholar   +1 more source