Radio-chemotherapy as a preoperative treatment for advanced rectal cancer. Evaluation of down-staging and morbidity [PDF]
, 2002 Background: The standard therapy for patients with clinically resectable rectal cancer is generally considered to be surgery, If the patient is diagnosed with advanced disease, postoperative radiochemotherapy (RCT) is usually recommended. In our study we
Dühmke, Eckhart +4 more
core +1 more source
JGH Open, 2022 Despite evidence of an increased prevalence of irritable bowel syndrome (IBS) in adults with inflammatory bowel disease (IBD) compared with the general population, the prevalence of IBS in children with IBD is unclear.
Lydia F Limbri +2 more
doaj +1 more source
Frontiers in Immunology, 2023 IntroductionClinical remission as a multicomponent treatment goal in severe asthma is being explored in clinical practice. This post hoc analysis used data from the REDES study to assess the proportion of patients with severe eosinophilic asthma ...
Ian Pavord +13 more
doaj +1 more source
The Diabetes Remission Clinical Trial (DiRECT): protocol for a cluster randomised trial [PDF]
, 2016 Background: Despite improving evidence-based practice following clinical guidelines to optimise drug therapy, Type 2 diabetes (T2DM) still exerts a devastating toll from vascular complications and premature death.
Adamson, Ashley +19 more
core +3 more sources
EFFICACY AND SAFETY OF TOFACITINIB IN PATIENTS WITH PSORIATIC ARTHRITIS IN REAL CLINICAL PRACTICE
Научно-практическая ревматология, 2020 Objective: to evaluate the clinical efficacy and safety of the targeted synthetic disease-modifying anti-rheumatic drug (DMARD) tofacitinib (TOFA; Yakvinus®) in patients with active psoriatic arthritis (PsA) at 12 and 24 weeks after starting treatment ...
E. Yu. Loginova +4 more
doaj +1 more source
Early identification of treatment non-response in first-episode psychosis
European Psychiatry, 2023 Background Approximately one-third of patients with psychotic disorders does not respond to standard antipsychotic treatments. Consensus criteria for treatment resistance (TR) may aid the identification of non-response and subsequent tailoring of ...
Kristin Fjelnseth Wold +10 more
doaj +1 more source
Chondrosarcoma of trachea: case report of successful surgical treatment of local recurrence
Опухоли головы и шеи, 2019 The study objective is to report a case of tracheal chondrosarcoma, which is a very rare malignant tumor. Only 18 cases have been described so far in English medical literature.Materials and methods.
Z. A.-G. Radzhabova +5 more
doaj +1 more source
Stanford neuromodulation therapy for treatment-resistant depression: a systematic review
Frontiers in Psychiatry, 2023 ObjectiveThis systematic review of randomized controlled studies (RCTs) and observational studies evaluated the efficacy and safety of stanford neuromodulation therapy (SNT) for patients with treatment-resistant depression (TRD).MethodsA systematic ...
Xian-Jun Lan +7 more
doaj +1 more source
Tight control is a way of optimizing the treatment of patients with rheumatoid arthritis
Научно-практическая ревматология, 2010 Objective: To evaluate the time course of changes in the symptoms of rheumatoid arthritis (RA) and its activity index during tight control in routine clinical practice. Subjects and methods.
Elvira Nikolayevna Otteva
doaj +1 more source
International study into the use of intermittent hormone therapy in the treatment of carcinoma of the prostate : A meta-analysis of 1446 patients [PDF]
, 2007 OBJECTIVE: To review pooled phase II data to identify features of different regimens of intermittent hormone therapy (IHT), developed to reduce the morbidity of treating metastatic prostate cancer, and which carries a theoretical advantage of delaying ...
Cuzick, Jack +6 more
core +1 more source