Results 51 to 60 of about 922,637 (337)

The significance of sleep quality in euthymic bipolar patients from Nigeria

South African Journal of Psychiatry, 2022
Background: Bipolar disorder is highly under-researched in Africa. Existing studies show that racial/ethnic disparities exist for sleep quality. Poor sleep quality in bipolar disorder causes significant morbidity and mortality even during periods of ...
Oluyomi Esan, Ayodele Fela-Thomas
doaj   +1 more source

Budesonide Orodispersible Tablets Maintain Remission in a Randomized, Placebo-Controlled Trial of Patients With Eosinophilic Esophagitis.

Gastroenterology, 2020
BACKGROUND & AIMS Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder. Swallowed topical-acting corticosteroids are effective in bringing active EoE into remission.
A. Straumann, A. Lucendo, S. Miehlke, M. Vieth, C. Schlag, L. Biedermann, C. Vaquero, C. Ciriza de Los Ríos, Christoph Schmoecker, A. Madisch, P. Hruz, J. Hayat, U. von Arnim, A. Bredenoord, S. Schubert, R. Mueller, R. Greinwald, A. Schoepfer, S. Attwood   +18 more
semanticscholar   +1 more source

Optimization of systemic juvenile arthritis treatment regimens with correction of tocilizumab intravenous administration according to data of observational retrospective study

Научно-практическая ревматология, 2019
Objective: to assess the possibility of using varying interval between intravenous infusions of tocilizumab (TCZ) as a tool for choosing the optimal treatment regimen in systemic juvenile arthritis (SJA).Subjects and methods.
M. I. Kaleda, I. P. Nikishina, O. M. Kostareva   +2 more
doaj   +1 more source

Advancing Therapeutic Targets in IBD: Emerging Goals and Precision Medicine Approaches

Pharmaceuticals
Inflammatory bowel diseases (IBD) including Crohn’s disease (CD) and ulcerative colitis (UC) are chronic, relapsing conditions characterized by dysregulated immune responses and persistent intestinal inflammation.
Lucia Centanni, Clelia Cicerone, Fabrizio Fanizzi, Ferdinando D’Amico, Federica Furfaro, Alessandra Zilli, Tommaso Lorenzo Parigi, Laurent Peyrin-Biroulet, Silvio Danese, Mariangela Allocca   +9 more
doaj   +1 more source

The efficacy and safety of apremilast in patients with psoriatic arthritis concurrent with comorbidity in clinical practice

Научно-практическая ревматология, 2019
Objective: to evaluate the clinical efficacy and safety of the targeted synthetic disease-modifying antirheumatic drug (DMARD) apremilast (AP; Otesla®) in patients with active psoriatic arthritis (PsA) at 14 and 26 weeks after starting the treatment and ...
E. Yu. Loginova, Yu. L. Korsakova, A. D. Koltakova, E. E. Gubar, P. L. Karpova, S. I. Glukhova, T. V. Korotaeva   +6 more
doaj   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Facts and myths about use of esketamine for treatment-resistant depression: a narrative clinical review

Frontiers in Psychiatry
Introduction and aimsTreatment-resistant depression (TRD) occurs when at least two different antidepressants, taken at the right dosage, for adequate period of time and with continuity, fail to give positive clinical effects. Esketamine, the S-enantiomer
Matteo Di Vincenzo, Vassilis Martiadis, Bianca Della Rocca, Eleonora Arsenio, Andrea D’Arpa, Antonio Volpicelli, Mario Luciano, Gaia Sampogna, Andrea Fiorillo   +8 more
doaj   +1 more source

Persistent clinical efficacy and safety of anti-tumour necrosis factor \textgreeka therapy with infliximab in patients with ankylosing spondylitis over 5 years: evidence for different types of response [PDF]

, 2008
Background: There is insufficient evidence for the long-term efficacy and safety of anti-tumour necrosis factor therapy in patients with ankylosing spondylitis (AS).
Alten, R., Baraliakos, X., Braun, J., Burmester, G., Fritz, C., Krause, A., Listing, J., Schewe, Stefan, Schneider, M., Sieper, J., Sörensen, H., Zeidler, H.   +11 more
core   +1 more source

An Expert Consensus Framework for Asthma Remission as a Treatment Goal.

Journal of Allergy and Clinical Immunology, 2019
With novel therapies in development, there is an opportunity to consider asthma remission as a treatment goal. In this Rostrum, we present a generalized framework for clinical and complete remission in asthma, on and off treatment, developed based on ...
Andrew Menzies-Gow, Mona Bafadhel, W. Busse, T. Casale, J. Kocks, I. Pavord, S. Szefler, P. Woodruff, A. de Giorgio-Miller, F. Trudo, M. Fagerås, C. Ambrose   +11 more
semanticscholar   +1 more source

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source