Results 51 to 60 of about 654,199 (289)

Switching from reference infliximab to CT-P13 in patients with inflammatory bowel disease: 12 months results [PDF]

, 2017
Background: Biological agents, such as infliximab, have transformed the outcomes of patients with immune-mediated inflammatory diseases. The advent of biosimilar treatment options such as CT-P13 promises to improve the availability of biological therapy,
Argüelles Arias, Federico, Castro Laria, Luisa, Guerra Veloz, María Fernanda, Maldonado Pérez, Belén, Merino Bohórquez, Vicente, Perea Amarillo, Raúl, Romero Gómez, Manuel, Vilches Arenas, Ángel   +7 more
core  

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Clinical remission and control in severe asthma: agreements and disagreements

Drugs in Context
Over the last two decades, we have witnessed great advancements in our understanding of the immunological pathways of asthma, leading to the development of targeted therapies, such as biologic drugs, that have radically and definitively changed the ...
Annamaria Bosi, Carlo Lombardi, Cristiano Caruso, Marcello Cottini, Ilaria Baglivo, Stefania Colantuono, Francesco Menzella   +6 more
doaj   +1 more source

Loss of efficacy of pasireotide after its re-administration: is there a reason why?

Rare Tumors, 2016
Pasireotide is a recently approved medical treatment for persistent or recurrent Cushing’s disease (CD). However, an escape from the initial successful response has not yet been described.
Stylianos Mandanas, Lemonia Mathiopoulou, Maria Boudina, Alexandra Chrisoulidou, Kalliopi Pazaitou-Panayiotou   +4 more
doaj   +1 more source

Tapered discontinuation vs. maintenance therapy of antipsychotic medication in patients with first-episode schizophrenia: Obstacles, findings, and lessons learned in the terminated randomized clinical trial TAILOR

Frontiers in Psychiatry, 2022
AimEvidence is insufficient regarding the consequences of discontinuing vs. maintaining antipsychotic medication in patients with first-episode schizophrenia. Our aim was to examine tapered discontinuation vs. maintenance treatment regarding remission of
Anne Emilie Stürup, Carsten Hjorthøj, Carsten Hjorthøj, Nikolai Albert, Nikolai Albert, Signe Dolmer, Merete Birk, Bjørn H. Ebdrup, Bjørn H. Ebdrup, Lene Falgaard Eplov, Heidi Jensen, Ditte Lammers Vernal, Helene Speyer, Ole Mors, Merete Nordentoft   +14 more
doaj   +1 more source

Clinical performance of an infliximab rapid quantification assay [PDF]

, 2017
Background: Therapeutic drug monitoring (TDM)-based algorithms can be used to guide infliximab (IFX) adjustments in inflammatory bowel disease (IBD) patients.
Afonso, Joana, Andrade, Patrícia, Caldeira, Paulo, Carneiro, Fátima, Carvalho, Diana, Coelho, Rosa, Dias, Cláudia Camila, Geboes, Karel, Gonçalves, Ana Rita, Gonçalves, Raquel, Lago, Paula, Lopes, Joanne, Lopes, Susana, Magro, Fernando, Meira, Tania, Ministro, Paula, Ramos, Jaime, Rosa, Isadora, Soares, João-Bruno, Sousa, Helena Tavares, Sousa, Paula, Vieira, Ana Isabel   +21 more
core   +2 more sources

Gemcitabine, Docetaxel, Melphalan, Carboplatin as Part of Sequential Cycles of High‐Dose Chemotherapy With Autologous Hematopoietic Stem‐Cell Rescue for Multiply Relapsed/Refractory Pediatric Germ Cell Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost, Olayinka Okeleji, Amr Elgehiny, Douglas Harrison, Cynthia Herzog, Jeremy Connors, Demetrios Petropoulos, Priti Tewari, Dristhi Ragoonanan, Yago Nieto, Irtiza N. Sheikh   +10 more
wiley   +1 more source

Correction of emotional and behavioral problems with children in the stage of remission using short-term strategic therapy methods

Психология и Психотерапия Семьи, 2017
The article is devoted to the topic of psychological work with emotional-behavioral disorders in children who have had oncological disease and are at the stage of remission.
Elena Fisun, Roman Miroshkin
doaj  

Thyroid peroxidase antibodies and their role in predicting outcomes in Graves’ disease treatment

Frontiers in Endocrinology
IntroductionGraves´ disease (GD) is the predominant cause of hyperthyroidism. Treatment options include antithyroid drugs (ATD), surgery, and radioactive iodine ablation (RI).
Klara Gewert, Klara Gewert, Geriolda Topi, Geriolda Topi, Tereza Planck, Tereza Planck, Jan Calissendorff, Jan Calissendorff   +7 more
doaj   +1 more source

Combined Treatment with Hyaluronic Acid and Mesalamine Protects Rats from Inflammatory Bowel Disease Induced by Intracolonic Administration of Trinitrobenzenesulfonic Acid

Molecules, 2017
Drugs such as mesalamine (5-ASA) are currently recommended for the treatment of inflammatory bowel disease (IBD). To reduce the frequency of their administration and improve their therapeutic effect, this study investigated the adhesion efficacy, wound ...
Chih-Tung Chiu, Sheng-Nan Kuo, Shao-Wen Hung, Cheng-Yao Yang   +3 more
doaj   +1 more source