Results 131 to 140 of about 1,471,327 (421)

Blood glucose level during induction phase chemotherapy in childhood acute lymphoblastic leukemia

Paediatrica Indonesiana, 2020
Background Steroids and L-asparaginase (L-Asp) are agents used in induction phase chemotherapy for childhood acute lymphoblastic leukemia (ALL). Both agents are often reported to have the side effect of hyperglycemia, and native L-Asp is also reported to
Nunki Andria, Annang Giri Moelyo, Muhammad Reza   +2 more
doaj   +1 more source

Two‐Year Follow‐Up of a Multidisciplinary Lifestyle Intervention for Rheumatoid Arthritis and Osteoarthritis

Arthritis Care &Research, Accepted Article.
Objective The Plants for Joints intervention (PFJ), including a whole‐food plant‐based diet, exercise, and stress reduction, reduced signs and symptoms of rheumatoid arthritis (RA) or metabolic syndrome‐associated hip or knee osteoarthritis (MSOA) compared to usual care. This study examined outcomes two years later. Methods After two 16‐week randomized
Carlijn A. Wagenaar, Wendy Walrabenstein, Marike van der Leeden, Franktien Turkstra, Martijn Gerritsen, Jos W.R. Twisk, Maarten Boers, Martin van der Esch, Henriët van Middendorp, Peter J.M. Weijs, Dirkjan van Schaardenburg   +10 more
wiley   +1 more source

Cost‐effectiveness of second‐line therapies in adults with chronic immune thrombocytopenia

American Journal of Hematology, Volume 98, Issue 1, Page 122-130, January 2023., 2023
Abstract Major options for second‐line therapy in adults with chronic immune thrombocytopenia (ITP) include splenectomy, rituximab, and thrombopoietin receptor agonists (TRAs). The American Society of Hematology guidelines recommend rituximab over splenectomy, TRAs over rituximab, and splenectomy or TRAs while noting a lack of evidence on the cost ...
George Goshua, Pranay Sinha, Natalia Kunst, Lauren Pischel, Alfred Ian Lee, Adam Cuker   +5 more
wiley   +1 more source

Molecular Predictors of Immunophenotypic Measurable Residual Disease Clearance in Acute Myeloid Leukemia [PDF]

, 2023
Measurable residual disease (MRD) is a powerful prognostic factor in acute myeloid leukemia (AML). However, pre-treatment molecular predictors of immunophenotypic MRD clearance remain unclear. We analyzed a dataset of 211 patients with pre-treatment next-
Abdel-Wahab, Omar, Arcila, Maria E, Barker, Juliet, Bewersdorf, Jan Philipp, Bowman, Robert L, Cai, Sheng F, Cho, Christina, Derkach, Andriy, Devlin, Sean, Dunbar, Andrew, Epstein-Peterson, Zachary D, Famulare, Christopher, Farnoud, Noushin, Gao, Qi, Getta, Bartlomiej, Geyer, Mark B, Giralt, Sergio A, Glass, Jacob L, Goldberg, Aaron D, Gyurkocza, Boglarka, Levine, Ross L, McGovern, Erin, Menghrajani, Kamal, Miles, Linde A, Pai, Nidhi, Papadopoulos, Esperanza B, Papaemmanuil, Elli, Patel, Minal A, Perales, Miguel-Angel, Robinson, Troy, Roshal, Mikhail, Schulman, Jessica, Shaffer, Brian C, Stahl, Maximilian, Stein, Eytan M, Tallman, Martin S, Taylor, Justin, Viny, Aaron D, Xiao, Wenbin, Zhang, Yanming   +39 more
core   +1 more source

Engineering Novel DNA Nanoarchitectures for Targeted Drug Delivery and Aptamer Mediated Apoptosis in Cancer Therapeutics

Advanced Functional Materials, EarlyView.
Designer DNA Architecture‐templated Drug Conjugates (DDA‐DCs) are comprised of a DNA nanomaterial decorated with multiple drug‐loaded DNA aptamers. DDA‐DCs use a combination of multiple aptamer types, each recognizing a different membrane protein to achieve precise targeting of cancer cells.
Abhisek Dwivedy, Dhyanesh Baskaran, Gaurav Sharma, Wei Hong, Dhanush Gandavadi, Abhichart Krissanaprasit, Joonsu Han, Yusheng Liu, Zack Zimmers, Tshepo Mafokwane, Ichrak Hayah, Neha Chauhan, Mengxi Zheng, Sherwood Yao, Keith Fraser, John S. Decker, Xiaohe Jin, Hua Wang, Adam D. Friedman, Xing Wang   +19 more
wiley   +1 more source

Combining CD34+ stem cell selection with prophylactic pathogen and leukemia directed T‐cell immunotherapy to simultaneously reduce graft versus host disease, infection, and leukemia recurrence after allogeneic stem cell transplant

American Journal of Hematology, Volume 98, Issue 1, Page 159-165, January 2023., 2023
Donor stem cell product undergoes CD34 stem cell selection. CD34 positive stem cells are used for transplantation. Pathogen‐ and leukemia‐specific T‐cells are manufactured from CD34 negative fraction and infused prophylactically 21 days after transplant.
David J. Gottlieb, Gaurav Sutrave, Wei Jiang, Selmir Avdic, Janine A. Street, Renee Simms, Leighton E. Clancy, Vicki Antonenas, Brian S. Gloss, Caroline Bateman, David C. Bishop, Kenneth P. Micklethwaite, Emily Blyth   +12 more
wiley   +1 more source

MESALAZINE PLACE IN THERAPY OF ULCERATIVE COLITIS

Медицинский совет, 2017
Preparations of 5-aminosalycil acid (Mesalazine) are used as the first-line therapy to induce remission if the UC activity is minimal and as the priority drugs for anti-recurrence therapy of patients with UC and are included in the Russian ...
I. G. Bakulin, M. I. Skalinskaya, E. V. Skazyvaeva   +2 more
doaj   +1 more source

Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus

Autoimmune Diseases, 2014
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with high morbidity if untreated. Sometimes, despite aggressive treatments, the disease remains active with cumulative organic damage.
F. Bonilla-Abadía, Nicolás Coronel Restrepo, G. Tobón, A. Echeverri, Evelyn Muñoz-Buitrón, A. Castro, Mercedes Andrade Bejarano, C. Cañas   +7 more
semanticscholar   +1 more source

Preleukemia: one name, many meanings. [PDF]

, 2017
Definition of preleukemia has evolved. It was first used to describe the myelodysplastic syndrome (MDS) with a propensity to progress to acute myeloid leukemia (AML). Individuals with germline mutations of either RUNX1, CEBPA, or GATA2 can also be called
Koeffler, HP, Leong, G
core  

Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]

, 2003
Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to ...
Chen, Xiao, Guenther, Wolfgang, Kolb, Hans-Jochem, Ledderose, Georg, Roskrow, Marie, Schleuning, Michael, Schmid, Christoph, Weber, Martin, Woiciechowski, Anja   +8 more
core   +1 more source