Results 201 to 210 of about 1,471,327 (421)

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

Advanced Science, EarlyView.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas R.M. Van Audenaerde   +3 more
wiley   +1 more source

Molecular remission with arsenic trioxide in patients with newly diagnosed acute promyelocytic leukemia [PDF]

, 2004
Thirty six APML patients achieving hematological remission with As2O3 were serially monitored using RT-PCR. Though only 5.5% achieved molecular remission at induction remission, 94.5% became negative during consolidation.
Balasubramanian, P., Chandy, M., George, B., Mathews, L., Shaji, R. V., Srivastava, A.   +5 more
core  

Neoadjuvant Chemotherapy With Cisplatin Up‐Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14‐Mediated EMT Activation

Advanced Science, EarlyView.
Oral squamous cell carcinoma cells exhibit upregulated expression of GSDMD upon exposure to low‐dose cisplatin chemotherapy, which subsequently interacts with MMP14 through its N‐terminal domain, activating the epithelial‒mesenchymal transition (EMT) process and promoting the lymph node metastasis of oral squamous cell carcinoma.
Zixian Huang, Qiming Jiang, Qianyu Zhang, Nan Lu, Xi Rui, Rui Chen, Yan Wang, Yuepeng Wang, Xiaoding Xu, Zhiquan Huang   +9 more
wiley   +1 more source

Inductive limit violates quasi-cocommutativity [PDF]

arXiv, 2010
We show that the inductive limit of a certain inductive system of quasi-cocommutative C$^{*}$-bialgebras is not quasi-cocommutative. This implies that the category of quasi-cocommutative C$^{*}$-bialgebras is not closed with respect to the inductive limit.
arxiv  

Collection and composition of autologous peripheral blood stem cells graft in patients with acute myeloid leukemia: influence on hematopoietic recovery and outcome [Skupljanje i sastav transplantata autolognih krvotvornih matičnih stanica periferne krvi u bolesnika s akutnom mijeloičnom leukemijom: utjecaj na hematološki oporavak i ishod] [PDF]

, 2010
Hematopoietic stem cell (HSC) transplantation is a standard approach in the treatment of hematological malignant diseases. For the last 15 years the main source of cells for trasplantation have been peripheral blood stem cells (PBSC).
Batinić, Drago, Bojanić, Ines, Dubravčić, Klara, Dušak, Vesna, Golubić-Ćepulić, Branka, Labar, Boris, Mazić, Sanja, Mrsić, Mirando, Nemet, Damir, Raos, Mirela, Sertić, Dubravka, Serventi-Seiwerth, Ranka   +11 more
core  

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

Advanced Science, EarlyView.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo, Yingsen Tang, Ling Zeng, Xiaomei You, Siweier Luo, Yufei Du, Le Wang, Liangchun Wang, Jianchuan Wang, Jinjin Chen, Yiming Zhou   +10 more
wiley   +1 more source

Costs associated with adverse events from remission induction for children with Acute Lymphoblastic Leukemia (ALL). [PDF]

BMC Health Serv Res, 2022
Mejía-Aranguré E, Reyes-López A, Juárez-Villegas LE, Hernández-Olivares YO, Saucedo-Campos AD, Hernández-Pliego G, Martínez-Valverde S, Barajas-Nava LA, Garduño-Espinosa J.   +8 more
europepmc   +1 more source

A Case of Minimally Differentiated Acute Leukemia (AML—M0) Complicated by Ventricle Thrombosis During Remission-induction [PDF]

, 2001
Yuji Nozaki, Hiroshi Sono, Mika Sakaguchi, Mitsuhiro Matsuda, Yasuhiro Maeda, Akihisa Kanamaru   +5 more
openalex   +1 more source

Fast pH‐Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes

Advanced Science, EarlyView.
Arsenic trioxide transformed acute promyelocytic leukemia therapy and shows promise against HIV. A new method to solubilize the mineral realgar produces different arsenic species depleting the main arsenic target, nuclear PML protein, and retaining effects on leukemic and HIV reservoir cells, while minimizing off‐target damage.
Bojana Lucic, Douglas Santana Franciscato, Helton Pereira Nogueira, Lara Gallucci, Alceu Totti Silveira Junior, Asmaa Mohamed Ismail, Millie Robinson, Teresa Dallinger, Claudia Gutfleisch, Jochen Kurz, Maytê Toledo, Jessica Dias da Silva Ferraz, Mohammad Tarek, Danilo Dias, Ricardo Sobhie Diaz, Mahmoud ElHefnawi, Mattia Forcato, Hugo P Monteiro, Marina Lusic, Iart Luca Shytaj, Andrea Savarino   +20 more
wiley   +1 more source

Real-life comparison of posaconazole versus fluconazole for primary antifungal prophylaxis during remission-induction chemotherapy for acute leukemia. [PDF]

J Assoc Med Microbiol Infect Dis Can, 2023
Dufresne SF, Bergeron J, Beauchemin S, Abou Chakra CN, Vadnais B, Bouchard P, Labbé AC, Laverdière M.   +7 more
europepmc   +1 more source