Minimally myelosuppressive regimen for remission induction in pediatric AML: long-term results of an observational study. [PDF]
Hu Y+21 more
europepmc +1 more source
This study introduces a novel transdermal delivery system of molecular hydrogen for postoperative pain relief and wound healing. This system utilizes sustained‐release photothermal microneedles to integrate hydrogen‐releasing nanoparticles and temperature‐responsive microspheres, achieving acid‐responsive hydrogen release and controlled drug release ...
Aining Zhang+8 more
wiley +1 more source
STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao+20 more
wiley +1 more source
Successful remission induction therapy with azacitidine and venetoclax for a treatment-naive elderly patient with ETP/myeloid mixed-phenotype acute leukemia: a case report. [PDF]
Huang K, Pang Y.
europepmc +1 more source
This study investigates plasma metabolomic biomarkers for rheumatoid arthritis (RA) development using longitudinal data from 209 RA patients and 56 individuals at risk. It also reveals metabolic signatures linked to severity, age, sex, and anti‐citrullinated protein autoantibody in RA.
Chenxi Zhu+21 more
wiley +1 more source
Remission induction in refractory, drug resistant pediatric PICALM::MLLT10+ B-cell acute lymphoblastic leukemia by venetoclax. [PDF]
Niedermayer A+11 more
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Age and remission induction therapy for acute myeloid leukemia: An analysis of data from the Korean acute myeloid leukemia registry. [PDF]
Yoo KH+9 more
europepmc +1 more source
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen+8 more
wiley +1 more source
Successful outcome of disseminated Candida tropicalis osteomyelitis on remission induction for childhood Philadelphia chromosome-positive acute lymphoblastic leukaemia-case report. [PDF]
Xie L, Long Q, Zhou G, Liu S, Wen FQ.
europepmc +1 more source