Results 221 to 230 of about 1,678,519 (353)

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

Advanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv, Yu Cao, Yuhan Wang, Yunhao Wu, Yingying Zhang, Kuanghao Ye, Xian Qiu, Qingfang Sun, Liuguan Bian, Halimureti Paerhati, Valerie Voon, Shikun Zhan, Bomin Sun   +12 more
wiley   +1 more source

Fatal visceral disseminated varicella zoster virus infection during initial remission induction therapy in a patient with lupus nephritis: a case report and review of the literature. [PDF]

CEN Case Rep
Takehara R, Ebihara I, Honda Y, Ooba N, Kurosawa H, Sato C, Ohtani H, Tsutsumi Y, Nose M, Kobayashi M.   +9 more
europepmc   +1 more source

Evaluation of the induction programme for beginning teachers [PDF]

, 2011

core  

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

Advanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra, Ibrahim M. Sayed, Souhrid Mukherjee, Honit Piplani, Aida Habtezion, Michael J. Rosen, Jospeh C. Wu   +6 more
wiley   +1 more source

Successful discontinuation of corticosteroids through remission induction therapy with benralizumab for chronic eosinophilic pneumonia. [PDF]

Respirol Case Rep
Kai Y, Kataoka R, Suzuki K, Nakamura E, Takano M, Muro S.   +5 more
europepmc   +1 more source

A phase 2 study incorporating sorafenib into the chemotherapy for older adults with FLT3-mutated acute myeloid leukemia: CALGB 11001 [PDF]

, 2017
Uy, Geoffrey L., Westervelt, Peter
core   +1 more source

Prognostic factors in children with acute myeloid leukaemia and excellent response to remission induction therapy

British Journal of Haematology, 2015
Seth E. Karol, E. Coustan-Smith, Xueyuan Cao, S. Shurtleff, S. Raimondi, J. Choi, Raul C. Ribeiro, G. Dahl, W. Bowman, J. Taub, B. Degar, W. Leung, J. Downing, C. Pui, J. Rubnitz, D. Campana, H. Inaba   +16 more
semanticscholar   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Subarachnoid Hemorrhaging with Multiple Cerebral Artery Stenoses after Initiating Remission Induction Therapy for Eosinophilic Granulomatosis with Polyangiitis. [PDF]

Intern Med
Yasuba H, Yamada H, Togo M, Matoba K, Yamamoto Kashihara E, Nishimura K, Sendo S, Ueda Y, Saegusa J.   +8 more
europepmc   +1 more source