Acute Myeloid Leukemia (AML): The Role of Intensive Induction Chemotherapy [PDF]
Intensive induction therapy-in acute myeloid leukemia (AML), as in some other systemic malignancies- is a strategy fundamentally different from post-remission strategies.
Thomas Büchner+27 more
doaj +1 more source
Successful treatment of idiopathic retroperitoneal fibrosis with combined immunosuppressive therapy [PDF]
Background/Aim. Idiopathic retroperitoneal fibrosis (IRF) is characterized by the fibroinflammatory periaortic tissue that affects the ureters, causing obstructive nephropathy and variable impairment of renal function.
Obrenčević Katarina+10 more
doaj +1 more source
Towards Outcome-Driven Patient Subgroups: A Machine Learning Analysis Across Six Depression Treatment Studies [PDF]
Major depressive disorder (MDD) is a heterogeneous condition; multiple underlying neurobiological substrates could be associated with treatment response variability. Understanding the sources of this variability and predicting outcomes has been elusive.
arxiv
Efficacy of adalimumab as second-line therapy in a pediatric cohort of crohn’s disease patients who failed infliximab therapy: The Italian society of pediatric gastroenterology, hepatology, and nutrition experience [PDF]
Background: Adalimumab (Ada) treatment is an available option for pediatric Crohn’s disease (CD) and the published experience as rescue therapy is limited.
Accomando S.+15 more
core +1 more source
Current concepts of radioimmonotherapy for lymphoma [PDF]
nema
Mihailović Jasna+2 more
doaj +1 more source
BACKGROUND There is evidence that shows that calcineurin inhibitors may be useful for the treatment of severe ulcerative colitis. However, evidence regarding the efficacy of tacrolimus for remission induction in this setting is scarce.
Juan LASA, Pablo OLIVERA
doaj +1 more source
Objective To describe successful therapeutic strategies in statin-induced anti-HMGCR myopathy. Methods Retrospective data from a cohort of 55 patients with statin-induced anti-HMGCR myopathy, sequentially stratified by the presence of proximal weakness ...
Alain Meyer+33 more
doaj +1 more source
The long-term remission of rheumatoid arthritis with a single cycle of rituximab [PDF]
Introduction. Rituximab selectively targets CD20+ B cells and presumably protects joints in rheumatoid arthritis. Complete remissions after a single treatment with rituximab, in some cases for longer than 1 year, are observed in only the minority of ...
Glišić Branislava, Knežević Bojana
doaj +1 more source
Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-κB Activation. [PDF]
Background & aimsBiotin is a water-soluble vitamin that is indispensable for human health. Biotin deficiency can cause failure-to-thrive, immunodeficiency, alopecia, dermatitis, and conjunctivitis.
Cahalan, Michael D+5 more
core
Changing therapeutic landscape - The last decade [PDF]
Undoubtedly the most important event in the previous decade in lymphoma treatment was the establishment of immunotherapy as a prime modality. Addition of rituximab improves survival in almost every group of patients with CD20+ tumors. This has led to the
Aurer, Igor
core +1 more source