Results 41 to 50 of about 94,635 (266)

Aminosalicylates for induction of remission or response in Crohn's disease [PDF]

Cochrane Database of Systematic Reviews, 2016
Randomized trials investigating the efficacy of aminosalicylates for the treatment of mildly to moderately active Crohn's disease have yielded conflicting results. A systematic review was conducted to critically examine current available data on the efficacy of sulfasalazine and mesalamine for inducing remission or clinical response in these patients ...
Wee-Chian, Lim, Yongjun, Wang, John K, MacDonald, Stephen, Hanauer   +3 more
openaire   +2 more sources

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Prevalence and predictors of sustained remission/low disease activity after discontinuation of induction or maintenance treatment with tumor necrosis factor inhibitors in rheumatoid arthritis: a systematic and scoping review

Arthritis Research & Therapy, 2023
Background To determine the prevalence of sustained remission/low disease activity (LDA) in patients with rheumatoid arthritis (RA) after discontinuation of tumor necrosis factor inhibitors (TNFi), separately in induction treatment and maintenance ...
Michael M. Ward, Nima Madanchi, Ali Yazdanyar, Nehal R. Shah, Florina Constantinescu   +4 more
doaj   +1 more source

Clinical Profile and Induction Outcome of Children with T-cell Acute Lymphoblastic Leukemia and T-cell Lymphoblastic Lymphoma

Pakistan Armed Forces Medical Journal, 2022
Objective: To study the clinical profile and induction outcome in children diagnosed with T-cell acute lymphoblastic leukaemia and lymphoblastic lymphoma. Study Design: Cross-sectional study.
Awais Arshed, Faran Nasarullah, Samra Shahid, Muhammad Tahir, Tanzeela Farah, Tariq Ghafoor   +5 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Recent advances in the management of antineutrophil cytoplasmic antibody-associated vasculitis

Indian Journal of Rheumatology, 2019
The prognosis of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) has remarkably improved from an almost uniformly fatal disease about three decades back, to a chronic manageable disease with survival rates in excess of 80 ...
Durga Prasanna Misra, G SRSN K Naidu, Aman Sharma   +2 more
doaj   +1 more source

Statin-induced anti-HMGCR myopathy: successful therapeutic strategies for corticosteroid-free remission in 55 patients

Arthritis Research & Therapy, 2020
Objective To describe successful therapeutic strategies in statin-induced anti-HMGCR myopathy. Methods Retrospective data from a cohort of 55 patients with statin-induced anti-HMGCR myopathy, sequentially stratified by the presence of proximal weakness ...
Alain Meyer, Yves Troyanov, Julie Drouin, Geneviève Oligny-Longpré, Océane Landon-Cardinal, Sabrina Hoa, Baptiste Hervier, Josiane Bourré-Tessier, Anne-Marie Mansour, Sara Hussein, Vincent Morin, Eric Rich, Jean-Richard Goulet, Sandra Chartrand, Marie Hudson, Jessica Nehme, Jean-Paul Makhzoum, Farah Zarka, Edith Villeneuve, Jean-Pierre Raynauld, Marianne Landry, Erin K. O’Ferrall, Jose Ferreira, Benjamin Ellezam, Jason Karamchandani, Sandrine Larue, Rami Massie, Catherine Isabelle, Isabelle Deschênes, Valérie Leclair, Hélène Couture, Ira N. Targoff, Marvin J. Fritzler, Jean-Luc Senécal   +33 more
doaj   +1 more source

Antibiotics for the induction and maintenance of remission in ulcerative colitis [PDF]

Cochrane Database of Systematic Reviews, 2020
Antibiotics have been considered to treat ulcerative colitis (UC) due to their antimicrobial properties against intestinal bacteria linked to inflammation. However, there are concerns about their efficacy and safety.To determine whether antibiotic therapy is safe and effective for the induction and maintenance of remission in people with UC.We searched
Gordon, Morris, Grafton-Clarke, Ciaran, Sinopoulou, Vassiliki, Akobeng, Anthony K   +3 more
openaire   +2 more sources

Improved Early Referral in Long‐Term Survivor Care With Institutional Standardized Practice Among Childhood Leukemia Survivors#

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark, Kayla L. Foster, Omar Shakeel, Mary C. Shapiro, Shawki L. Qasim, ZoAnn Dreyer, Eric S. Schafer, Ashley M. Butler, Austin L. Brown, Maria Monica Gramatges   +9 more
wiley   +1 more source

The Role of Mycophenolate Mofetil for the Induction of Remission in ANCA-Associated Vasculitis: A Meta-Analysis

Frontiers in Medicine, 2021
Objectives: The successful introduction of mycophenolate mofetil (MMF) as a treatment for renal allograft reduced the incidence of acute rejection. The inspiring effects obtained by the MMF have led to an evaluation of its therapeutic potency on ANCA ...
Anji Xiong, Chen Xiong, Guancui Yang, Yu Shuai, Deng Liu, Linqian He, Zepeng Guo, Liangwen Zhang, Yi Liu, Yuan Yang, Beibei Cui, Shiquan Shuai   +11 more
doaj   +1 more source