Results 21 to 30 of about 101,889 (202)

Etrolizumab for induction of remission in ulcerative colitis

Cochrane Database of Systematic Reviews, 2015
Etrolizumab (rhuMAb beta7) is an anti-integrin that selectively targets the β7 subunits of the α4β7 and αEβ7 integrins, which are involved in the pathogenesis of ulcerative colitis.The objectives of this review were to assess the efficacy and safety of etrolizumab for induction of remission in ulcerative colitis.We searched PubMed, MEDLINE, EMBASE, and
Greg, Rosenfeld, Claire E, Parker, John K, MacDonald, Brian, Bressler   +3 more
openaire   +3 more sources

An operational definition of primary refractory acute myeloid leukemia allowing early identification of patients who may benefit from allogeneic stem cell transplantation

Haematologica, 2016
Up to 30% of adults with acute myeloid leukemia fail to achieve a complete remission after induction chemotherapy - termed primary refractory acute myeloid leukemia.
Paul Ferguson, Robert K. Hills, Angela Grech, Sophie Betteridge, Lars Kjeldsen, Michael Dennis, Paresh Vyas, Anthony H. Goldstone, Donald Milligan, Richard E. Clark, Nigel H. Russell, Charles Craddock   +11 more
doaj   +1 more source

Probiotics for induction of remission in Crohn's disease [PDF]

Cochrane Database of Systematic Reviews, 2008
Crohn's disease has a high morbidity and there is no known cure. Current treatments have multiple side effects and an effective treatment with minimal side effects is desired. Probiotics have been proposed as such a treatment but their efficacy is undetermined.
Andrew D, Butterworth, Adrian G, Thomas, Anthony Kwaku, Akobeng   +2 more
openaire   +2 more sources

A Link between cholesterol levels and phenobarbital induction of cytochromes P450 [PDF]

, 2002
Squalestatin1 (SQ1), a potent inhibitor of squalene synthase produced a dose-dependent induction of cytochromes P450 CYP2H1 and CYP3A37 mRNAs in chicken hepatoma cells. The effect of SQ1 was completely reversed by 25-hydroxycholesterol.
Christoph Handschin, Handschin, C., Meyer, U. A., Urs A. Meyer, Kaufmann, M., Jean-Claude Ourlin, Michel Kaufmann, Ourlin, J. -C.   +7 more
core   +1 more source

Predictors of remission with etanercept-methotrexate induction therapy and loss of remission with etanercept maintenance, reduction, or withdrawal in moderately active rheumatoid arthritis: results of the PRESERVE trial

Arthritis Research & Therapy, 2018
Background The aim was to analyze characteristics that predict remission induction and subsequent loss of remission in patients with moderately active rheumatoid arthritis (RA) who received full-dose combination etanercept plus methotrexate induction ...
Josef S. Smolen, Annette Szumski, Andrew S. Koenig, Thomas V. Jones, Lisa Marshall   +4 more
doaj   +1 more source

End of induction treatment outcomes with a novel cyclophosphamide-based regimen for severe lupus nephritis: Single-center experience from South India

Indian Journal of Rheumatology, 2020
Background: Cyclophosphamide is commonly used along with pulse steroids for induction immunosuppression treatment of severe forms of lupus nephritis (LN).
V Jayaprakash, T Dineshkumar, J Dhanapriya, D Rajasekar, R Sakthirajan, T Balasubramaniyan, Anila A Kurien, N Gopalakrishnan   +7 more
doaj   +1 more source

Successful treatment of idiopathic retroperitoneal fibrosis with combined immunosuppressive therapy [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. Idiopathic retroperitoneal fibrosis (IRF) is characterized by the fibroinflammatory periaortic tissue that affects the ureters, causing obstructive nephropathy and variable impairment of renal function.
Obrenčević Katarina, Petrović Dejan, Aleksić Predrag, Petrović Marijana, Rančić Nemanja, Jovanović Dragan, Nikolić Bojan, Mijušković Mirjana, Vavić Neven, Ignjatović Ljiljana, Maksić Đoko   +10 more
doaj   +1 more source

Economic analysis of oral posaconazole prophylaxis in acute myeloid leukemia during remission induction in Turkey. [PDF]

North Clin Istanb, 2020
OBJECTIVE: Invasive fungal infections (IFI) are important and trending causes of mortality in patients with acute leukemia, especially during the remission induction.
Umit EG, Baysal M, Kirkizlar HO, Demir AM.   +3 more
europepmc   +2 more sources

Influence of Cytokines and Autologous Lymphokine-Activated Killer Cells on Leukemic Bone Marrow Cells and Colonies in AML [PDF]

, 2001
We have already shown that cytokine cocktails (IL-1 beta, IL-3, IL-6, SCF, GM-CSF) and/or lymphokine-activated killer (LAK) cells can reduce the amounts of clonal, CD34-positive mononuclear bone marrow cells (BM-MNC) in acute myeloid leukemia (AML).
Gerhartz, Helmut Heinrich, Schmetzer, Helga Maria, Braun, Susanne Walburg   +2 more
core   +1 more source

Adalimumab for induction of remission in Crohn's disease

Cochrane Database of Systematic Reviews, 2017
Adalimumab is an IgG1 monoclonal antibody that targets and blocks tumor necrosis factor-alpha, a pro-inflammatory cytokine involved in the pathogenesis of Crohn's disease (CD). A significant proportion of people with CD fail conventional therapy or therapy with biologics or develop significant adverse events.
Mohamad, Abbass, Jeremy, Cepek, Claire E, Parker, Tran M, Nguyen, John K, MacDonald, Brian G, Feagan, Reena, Khanna, Vipul, Jairath   +7 more
openaire   +4 more sources