Results 61 to 70 of about 94,635 (266)

Certolizumab pegol for induction of remission in Crohn's disease

Cochrane Database of Systematic Reviews, 2017
Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract, and immune response modulation is the main treatment strategy to induce remission in active CD. Certolizumab pegol (CZP) is a tumor necrosis factor-alfa (TNF-α) inhibitor which regulates impaired immune response.The primary objectives were to evaluate the efficacy and
Hajime, Yamazaki, Ryuhei, So, Katsuyoshi, Matsuoka, Taku, Kobayashi, Shinichiro, Shinzaki, Minoru, Matsuura, Shinji, Okabayashi, Yuki, Kataoka, Yasushi, Tsujimoto, Toshi A, Furukawa, Norio, Watanabe   +10 more
openaire   +4 more sources

Infection during remission induction in childhood leukaemia [PDF]

Archives of Disease in Childhood, 1980
We have analysed our experience in the management of suspected infection in a group of 221 children with acute leukaemia undergoing induction of first remission. Patients with suspected infection received early empirical antibiotic therapy with cephalothin and gentamicin pending results of bacteriological investigations.
J M, Chessells, A D, Leiper
openaire   +2 more sources

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin, Usanarat Anurathapan, Rawiwan Roongpraiwan, Potchanee Dandamrongrak, Siriporn Nakhonchai, Pawin Numthavaj, Vilawan Chirdkiatgumchai   +6 more
wiley   +1 more source

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

Efficacy and safety of medical therapies in microscopic colitis: a systematic review and network meta-analysis

Therapeutic Advances in Gastroenterology, 2023
Background: The mainstay of treatment for microscopic colitis (MC) is budesonide. However, the optimal formulation and dosage of budesonide to induce and maintain remission has not yet been clearly demonstrated.
Aditi Kumar, George Hiner, Matthew J. Brookes, Jonathan P. Segal   +3 more
doaj   +1 more source

Fish oil for induction of remission in ulcerative colitis

Cochrane Database of Systematic Reviews, 2006
Fish oil supplements, which are rich in n-3 fatty acids, may reduce inflammation, decrease the need for anti-inflammatory drugs, and promote normal weight gain in people with ulcerative colitis.This review evaluates the efficacy of fish oil for induction of remission in ulcerative colitis using all available randomised controlled trials.The Cochrane ...
De Ley, Maartje, de Vos, Rien, Hommes, Daniel W, Stokkers, Pieter C   +3 more
openaire   +2 more sources

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Effectiveness of tacrolimus therapy in refractory ulcerative colitis compared to infliximab with propensity score matching

Scientific Reports
There is insufficient evidence comparing the outcomes of tacrolimus-based remission induction therapy with infliximab in refractory ulcerative colitis (UC) and evidence regarding optimal strategies after tacrolimus-based remission induction therapy.
Takeo Yoshihara, Takahiro Amano, Shinichiro Shinzaki, Yuri Tsujii, Akiko Asakura, Taku Tashiro, Mizuki Tani, Yuriko Otake-Kasamoto, Takuya Yamada, Yuko Sakakibara, Naoto Osugi, Shuji Ishii, Satoshi Egawa, Manabu Araki, Yuki Arimoto, Masanori Nakahara, Yoko Murayama, Ichizo Kobayashi, Kazuo Kinoshita, Hiroyuki Ogawa, Satoshi Hiyama, Narihiro Shibukawa, Masato Komori, Yorihide Okuda, Takashi Kizu, Tetsuhisa Kitamura, Minoru Kato, Yoshiki Tsujii, Takahiro Inoue, Hideki Iijima, Yoshito Hayashi, Tetsuo Takehara   +31 more
doaj   +1 more source

MESALAZINE PLACE IN THERAPY OF ULCERATIVE COLITIS

Медицинский совет, 2017
Preparations of 5-aminosalycil acid (Mesalazine) are used as the first-line therapy to induce remission if the UC activity is minimal and as the priority drugs for anti-recurrence therapy of patients with UC and are included in the Russian ...
I. G. Bakulin, M. I. Skalinskaya, E. V. Skazyvaeva   +2 more
doaj   +1 more source