Results 81 to 90 of about 1,678,519 (353)

Delivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effects [PDF]

, 2013
Mesenchymal stem cells (MSCs) are able to infiltrate tumor tissues and thereby effectively deliver gene therapeutic payloads. Here, we engineered murine MSCs (mMSCs) to express a secreted form of the TNF-related apoptosis-inducing ligand (TRAIL), which ...
A Ashkenazi, A Ashkenazi, A Chuntharapai, A Mohr, A Mohr, A Mohr, A Mohr, A Nakamizo, A Peister, AM van der Sloot, B Hall, C Buneker, CR Reis, D Sampath, D Stadel, DR Camidge, EW Duiker, FP Barry, GS Wu, GS Wu, I Nicoletti, J Lemke, J Luetzkendorf, JW Schymkowitz, K Ichikawa, K Papenfuss, L Zhang, LG Menon, LS Sasportas, M MacFarlane, M Vogler, M Vogler, M Vogler, ME Davis, MH Kim, MR Loebinger, MR Sprick, RM Zwacka, RW Johnstone, SB Bratton, SJ Braeuer, SM Albarenque, SM Kim, T Trarbach, TK Oost, TM Ganten, TS Griffith   +46 more
core   +1 more source

Usefulness of fecal calprotectin for the early prediction of short-term outcomes of remission-induction treatments in ulcerative colitis in comparison with two-item patient-reported outcome

PLoS ONE, 2017
Background Fecal calprotectin (FC) is well accepted as a non-invasive biomarker which objectively reflects colonic inflammation in ulcerative colitis (UC). However, its value as a marker of response during the early phase of remission induction treatment
T. Toyonaga, Taku Kobayashi, M. Nakano, E. Saito, S. Umeda, Shinji Okabayashi, R. Ozaki, T. Hibi   +7 more
semanticscholar   +1 more source

Clinical performance of an infliximab rapid quantification assay [PDF]

, 2017
Background: Therapeutic drug monitoring (TDM)-based algorithms can be used to guide infliximab (IFX) adjustments in inflammatory bowel disease (IBD) patients.
Afonso, Joana, Andrade, Patrícia, Caldeira, Paulo, Carneiro, Fátima, Carvalho, Diana, Coelho, Rosa, Dias, Cláudia Camila, Geboes, Karel, Gonçalves, Ana Rita, Gonçalves, Raquel, Lago, Paula, Lopes, Joanne, Lopes, Susana, Magro, Fernando, Meira, Tania, Ministro, Paula, Ramos, Jaime, Rosa, Isadora, Soares, João-Bruno, Sousa, Helena Tavares, Sousa, Paula, Vieira, Ana Isabel   +21 more
core   +2 more sources

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

All That Bleeds Is Not Infliximab-Refractory Ulcerative Colitis

Canadian Journal of Gastroenterology, 2009
The role of biological agents in moderate to severe ulcerative colitis has been shown to be effective in the induction of clinical remission. However, the role of infliximab therapy for induction of remission in patients with fulminant colitis is ...
JK Law, B Salh, EM Yoshida
doaj   +1 more source

The Role of Mycophenolate Mofetil for the Induction of Remission in ANCA-Associated Vasculitis: A Meta-Analysis

Frontiers in Medicine, 2021
Objectives: The successful introduction of mycophenolate mofetil (MMF) as a treatment for renal allograft reduced the incidence of acute rejection. The inspiring effects obtained by the MMF have led to an evaluation of its therapeutic potency on ANCA ...
Anji Xiong, Chen Xiong, Guancui Yang, Yu Shuai, Deng Liu, Linqian He, Zepeng Guo, Liangwen Zhang, Yi Liu, Yuan Yang, Beibei Cui, Shiquan Shuai   +11 more
doaj   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Switching from reference infliximab to CT-P13 in patients with inflammatory bowel disease: 12 months results [PDF]

, 2017
Background: Biological agents, such as infliximab, have transformed the outcomes of patients with immune-mediated inflammatory diseases. The advent of biosimilar treatment options such as CT-P13 promises to improve the availability of biological therapy,
Argüelles Arias, Federico, Castro Laria, Luisa, Guerra Veloz, María Fernanda, Maldonado Pérez, Belén, Merino Bohórquez, Vicente, Perea Amarillo, Raúl, Romero Gómez, Manuel, Vilches Arenas, Ángel   +7 more
core  

Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey [PDF]

, 2017
Background: Diet is strongly associated with the aetiology of Crohn’s Disease (CD) and exclusive enteral nutrition (EEN) is the primary induction treatment in paediatric CD.
Buchanan, Elaine, Curtis, Lee, Garrick, Vikki, Gaya, Daniel R., Gerasimidis, Konstantinos, Hansen, Richard, Hay, Jacqueline, Laird, Susan, Munro, Joanna, Russell, Richard K., Svolos, Vaios   +10 more
core   +2 more sources

Intravenous pulse methylprednisolone for induction of remission in severe ANCA associated Vasculitis: a multi-center retrospective cohort study

BMC Nephrology, 2019
BackgroundIntravenous pulse methylprednisolone (MP) is commonly included in the management of severe ANCA associated vasculitis (AAV) despite limited evidence of benefit.
Dimitrios Chanouzas, J. McGregor, P. Nightingale, A. Salama, W. Szpirt, N. Basu, M. Morgan, Caroline Poulton, J. Draibe, E. Krarup, P. Dospinescu, J. Dale, W. Pendergraft, Keegan Lee, M. Egfjord, S. Hogan, L. Harper   +16 more
semanticscholar   +1 more source