Results 191 to 200 of about 142,915 (338)
mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim +4 more
wiley +1 more source
Combined models of violent conflict and natural hazards improve predictions of household mobility in Bangladesh. [PDF]
Leis M, Petrova K.
europepmc +1 more source
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan +11 more
wiley +1 more source
Association of remittances with skilled delivery in Uganda, 2019/2020. [PDF]
Ducille C +4 more
europepmc +1 more source
Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao +11 more
wiley +1 more source
Diaspora as partners: strengthening resilience of health systems and communities amidst aid volatility. [PDF]
Dafallah A +2 more
europepmc +1 more source
This work proposes a high static magnetic field (HSMF) driven dual‐low‐dimension strategy for fabricating magnetic‐dielectric heterostructure (Fe3O4@MoS2) chains with programmable lengths. The constructed successive magnetic‐dielectric synergy, arising from uniaxial anisotropy‐enhanced magnetic response and abundant heterointerfaces that boost ...
Zhuolin Li +5 more
wiley +1 more source
Migration dynamics and nutritional outcomes in a lower middle-income country: evidence from Vietnam. [PDF]
Vo TT, Bich Hien NT, Huyen TM, Tan VN.
europepmc +1 more source
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk +9 more
wiley +1 more source

