Results 211 to 220 of about 33,311 (296)

Supporting Aged Care Worker Wellbeing: A Qualitative Document Analysis of the Strengthened Aged Care Quality Standards

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Aged care work is physically and emotionally demanding. Workers can feel disempowered, vulnerable and at increased risk of experiencing work‐related stress. This in turn can result in sub‐optimal care and staff shortages. This study aimed to investigate what provisions exist within Australia's strengthened Aged Care Quality Standards to ...
Sharon Stoddart   +11 more
wiley   +1 more source

General Practice Utilisation for Adults With Neurological Disability Who Are National Disability Insurance Scheme Participants in Australia

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Most adults with neurological disability rely on general practitioners for managing and preventing health complications. This study analysed patterns of general practice service utilisation among National Disability Insurance Scheme (NDIS) participants with neurological disability and compared these with people who are not NDIS participants ...
Stacey Oliver   +8 more
wiley   +1 more source

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

open access: yesAngewandte Chemie, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang   +15 more
wiley   +2 more sources

Clinical Longitudinal Evaluation After Regimen Stop (CLEAR) of Dupilumab in Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Long‐term management strategies for severe chronic rhinosinusitis with nasal polyps (CRSwNP) increasingly include biologic therapy targeting Type 2 inflammation. However, data on outcomes after complete discontinuation of dupilumab following sustained disease control are scarce.
Patrick Huber   +7 more
wiley   +1 more source

Construction and evaluation of a chronic arthritis animal model induced by persistent activation of toll‐like receptors via lipopolysaccharide stimulation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We constructed a novel systemic juvenile idiopathic arthritis mouse model (LC) by introducing sustained TLR4 activation into the collagen‐induced arthritis model. The LC model effectively recapitulates human sJIA‐like systemic inflammation while revealing a critical dissociation between systemic immune activation and joint damage.
Fengming Li   +4 more
wiley   +1 more source

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