Results 171 to 180 of about 20,963 (287)

Skeletal muscle glucocorticoid receptor density and insulin resistance. [PDF]

, 2002
Chapman, Karen E, Lithell, Hans O, McKeigue, Paul M, Reynolds, Rebecca M, Seckl, Jonathan R, Walker, Brian R   +5 more
core   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Remnant cholesterol in chronic obstructive pulmonary disease-phenotypes and pharmacotherapy matter. [PDF]

J Thorac Dis
Hao J, Gu X.
europepmc   +1 more source

A rebuttal--the Rsal polymorphism in the alpha-fibrinogen gene and response of plasma fibrinogen to physical training. [PDF]

, 2001
Cook, D, Davey, G, McKeigue, P
core   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Association of remnant cholesterol with cardiovascular events and mortality in biopsy-proven diabetic kidney disease. [PDF]

Front Endocrinol (Lausanne)
Hu Q, Chen L, Xing L, Xu Y, Xiong J, Tang Y.   +5 more
europepmc   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Remnant Cholesterol as a Predictor of Target-Vessel Failure in Patients With In-Stent Restenosis. [PDF]

Rev Cardiovasc Med
Kong XH, Lv ZH, Wang YF, Sun YD, Xu T, You W, Meng PN, Wu XQ, Wu ZM, Jia HB, Ye F.   +10 more
europepmc   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Remnant cholesterol and lipid ratios predict the relapse of neuromyelitis optica spectrum disorder. [PDF]

Lipids Health Dis
Wang Z, Huang T, Cui B, Cheng J, Pang X, Zhang M, Guo J, Meng H.   +7 more
europepmc   +1 more source