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Contribution of remnant cholesterol to cardiovascular risk
Journal of Internal Medicine, 2020AbstractBackgroundRemnant cholesterol in triglyceride‐rich lipoproteins is associated observationally and genetic, causally with increased risk of atherosclerotic cardiovascular disease in healthy individuals.ObjectivesWe tested the hypothesis that an unmet medical need exists in individuals with high nonfasting remnant cholesterol and prior ...
A. Langsted +2 more
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Remnant cholesterol, vascular risk, and prevention of atherosclerosis
Clínica e Investigación en Arteriosclerosis (English Edition), 2023In patients who have achieved optimal LDL-C control, there remains a residual risk of atherothrombotic cardiovascular disease (ACVD) related to alterations in lipid metabolism, where alterations in triglyceride-rich lipoproteins and the cholesterol they contain, called remnant cholesterol, play a major role.
Xavier, Pintó +3 more
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Remnant cholesterol and ischemic heart disease
Current Opinion in Lipidology, 2014To review recent advances in the field of remnant cholesterol as a contributor to the development of ischemic heart disease (IHD).Epidemiologic, mechanistic, and genetic studies all support a role for elevated remnant cholesterol (=cholesterol in triglyceride-rich lipoproteins) as a contributor to the development of atherosclerosis and IHD ...
Varbo, Anette, Nordestgaard, Børge G
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Remnant cholesterol in patients admitted for acute coronary syndromes
European Journal of Preventive Cardiology, 2022AbstractBackgroundRemnant cholesterol has been identified as one of leading lipid values associated with the incidence of coronary heart disease. There is scarce evidence on its distribution and prognostic value in acute coronary syndrome (ACS) patients.Methods and resultsWe included all consecutive patients admitted for ACS in two different centres ...
Alberto Cordero +9 more
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Genetics of remnant cholesterol
Current Opinion in LipidologyPurpose of review Remnant cholesterol is receiving increasing attention as a target to reduce residual atherosclerotic cardiovascular disease (ASCVD) risk in individuals already treated with statins. New therapeutic options as antisense oligonucleotides, small interfering RNA, and monoclonal antibodies allow specific targeting ...
Anders B, Wulff, Børge G, Nordestgaard
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Triglyceride-rich lipoproteins, remnant-cholesterol, and atherosclerotic cardiovascular disease
Current Opinion in Lipidology, 2023Purpose of review Despite indisputable role of LDL-C lowering, a considerable residual risk for atherosclerotic cardiovascular disease (ASCVD) persists. The precise mechanism(s) underlying this phenomenon remain unclear. Triglyceride-rich lipoproteins (TRL) appear to be one of the main mediators, based on the genetic and ...
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Relationship between Serum Bilirubin and Remnant Lipoprotein Cholesterol Level
Clinical Laboratory, 2013Bilirubin has antioxidant properties and is known to have a role in the prevention of cardiovascular disease. Bilirubin is known to be negatively associated with serum parameters related to atherosclerosis. Triglyceride-rich lipoprotein is known to play an important role in the progression of atherosclerosis.
Toshinori, Kamisako +2 more
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A NEW LARGE CHYLOMICRON REMNANT FROM CHOLESTEROL‐FED RABBITS
Australian Journal of Experimental Biology and Medical Science, 1978SummaryThe lipoproteins of density < 1 063 g/ml of cholesterol‐fed rabbits were subjected to analytical ultracentrifugation. and many rabbits two peaks were found in the very low density (Sf > 20) portion of the lipoprotein spectrum. They were isolated by preparative ultracentrifugation and analysed.
A G, Bosanquet +2 more
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What is ‘remnant cholesterol’?
European Heart Journal, 2023Paulina E Stürzebecher +2 more
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