This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber +12 more
wiley +1 more source
Systematic meta-review on migrant healthcare access: Language barriers and the role of translation. [PDF]
Díaz-Millón M, Olvera-Lobo MD.
europepmc +1 more source
Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin +19 more
wiley +1 more source
Preferences and Perceptions of Training Models in Global Surgery With a Focus on Orthopedics: A Scoping Review. [PDF]
Kaur H +3 more
europepmc +1 more source
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang +9 more
wiley +1 more source
Bilateral haemorrhagic cysts on ultrasound with an intraoperative diagnosis of spontaneous bilateral unruptured ectopic pregnancies: A case report with management challenges in a rural setting. [PDF]
Horsburgh E, Black P.
europepmc +1 more source
Remote healthcare interpreting: challenges & strategies
Abstract: The rising diversity and multilingual nature of our societies create a great need for language mediation (Tipton & Furmanek, 2016) that can simply not be fulfilled with onsite interpreting services only (González Rodríguez & Spinolo, 2017, p. 242).
openaire +1 more source
Nanozymes for Energy and Environmental Sustainability
At present, the widely used nanozymes are oxidoreductase and hydrolase, which have proved to have great application prospects in energy and environment. ABSTRACT Nanozymes have shown remarkable promise in addressing pressing challenges in energy and environmental sustainability.
Xiaoqi Li, Jinxing Chen, Shaojun Dong
wiley +1 more source
Efficiency of remote videoconference-assisted ultrasound education: comparison with standard classroom training. [PDF]
Vatsvåg V +4 more
europepmc +1 more source

