Results 131 to 140 of about 2,439,509 (314)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
[[alternative]]Arsenic Removal by Coagulation with Alum
, 2010 [[abstract]]Bench-scale studies were conducted with synthetic freshwaters to assess the applicability of coagulation processes to meet a lower standard for arsenic in drinking water.
陳本源;談珮華
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Fate and removal of pharmaceuticals during sewage treatment [PDF]
, 2005 Pharmaceuticals, personal care products and their metabolites are continuously entering the environment through many routes, especially from the effluent of sewage treatment plants.
Thompson, Andrew
core
Effect of Temperature and Pressure on Removal of Fluoride from Groundwater Using Nanofiltration
Journal of Mazandaran University of Medical Sciences, 2018 Background and purpose: Fluoride is a major mineral pollutant in groundwater. Long-term exposure to high concentration of fluoride in drinking water causes dental fluorosis, skeletal and non-skeletal fluorosis. Therefore, highly efficient water treatment
Mohammad Mahdi Emamjomeh +4 more
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A comparative study of different strategies of batch effect removal in microarray data: a case study of three datasets [PDF]
, 2013 Batch effects refer to the systematic non-biological variability that is introduced by experimental design and sample processing in microarray experiments.
Ding, Fei
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source