Results 81 to 90 of about 2,124,411 (292)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Effects of Removal on a Lightly Exploited Coyote Population in Eastern Nevada

open access: yesHuman-Wildlife Interactions, 2017
Coyote (Canis latrans) removal is a common, yet controversial, management practice to increase game populations throughout the West. I studied the effect of removal on coyote populations in eastern Nevada from 2004 to 2008 and reviewed 27 available ...
Patrick J. Jackson
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Uso da cinza da casca do arroz (CCA) obtida da geração de energia térmica como adsorvente de Zn(II) em soluções aquosas Use of rice husk ash (RHA) obtained from thermal energy generation as Zn (II) adsorbent in aqueous solutions

open access: yesQuímica Nova, 2009
The removal study was conducted using 1.00 g of the rice husk ash (RHA) and 20.0 mL solution with concentrations in the range of 10-1000 mg/L of Zn(II).
Thiago Faheina Chaves   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Functionalization of Na2Ca2Si3O9/Ca8Si5O18 Nanostructures with Chitosan and Terephthalaldehyde Crosslinked Chitosan for Effective Elimination of Pb(II) Ions from Aqueous Media

open access: yesInorganics
Lead poses significant health risks to humans, including neurological and developmental impairments, particularly in children. Additionally, lead pollution in the environment can contaminate soil, water, and air, endangering wildlife and ecosystems ...
Eida S. Al-Farraj   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Adsorptive removal of anionic dye from aqueous solutions using powdered and calcined vegetables wastes as low-cost adsorbent

open access: yesArab Journal of Basic and Applied Sciences, 2018
In this study, we describe a behaviour comparison between powdered and calcined adsorbents prepared from vegetables waste of Persea species to remove Eriochrome Black T as anionic dye from aqueous solutions. Potential capabilities of these two adsorbents
El Kassimi Aziz   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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