Results 161 to 170 of about 4,080,709 (367)

TGF-β/Smad signaling in renal fibrosis

open access: yesFrontiers in Physiology, 2015
TGF-β (transforming growth factor-β) is well identified as a central mediator in renal fibrosis. TGF-β initiates canonical and non-canonical pathways to exert multiple biological effects. Among them, Smad signaling is recognized as a major pathway of TGF-
Xiao-ming Meng, P. Tang, Jun Li, H. Lan
semanticscholar   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Renal recovery after acute kidney injury

open access: yesIntensive Care Medicine, 2017
Acute kidney injury (AKI) is a frequent complication of critical illness and carries a significant risk of short- and long-term mortality, chronic kidney disease (CKD) and cardiovascular events.
L. Forni   +8 more
semanticscholar   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

Editorial: Prevention, assessment and treatment of clinical issues related to endurance exercise and sports

open access: yesFrontiers in Physiology, 2023
Daniel Rojas-Valverde   +6 more
doaj   +1 more source

Pathophysiological Mechanisms of Renal Fibrosis: A Review of Animal Models and Therapeutic Strategies.

open access: yesIn Vivo, 2017
Chronic kidney disease (CKD) is a long-term condition in which the kidneys do not work correctly. It has a high prevalence and represents a serious hazard to human health and estimated to affects hundreds of millions of people.
A. Nogueira, M. J. Pires, P. Oliveira
semanticscholar   +1 more source

Towards Fine-grained Renal Vasculature Segmentation: Full-Scale Hierarchical Learning with FH-Seg [PDF]

open access: yesarXiv
Accurate fine-grained segmentation of the renal vasculature is critical for nephrological analysis, yet it faces challenges due to diverse and insufficiently annotated images. Existing methods struggle to accurately segment intricate regions of the renal vasculature, such as the inner and outer walls, arteries and lesions.
arxiv  

THE RENAL ELIMINATION OF BILIRUBIN [PDF]

open access: bronze, 1922
Herbert A. Haessler   +2 more
openalex   +1 more source

AAPM Task Group No. 249.B—Essentials and guidelines for clinical medical physics residency training program

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency training has become integrated into the eligibility criteria for most medical physics certification bodies.
Jonathon A. Nye   +16 more
wiley   +1 more source

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