Results 261 to 270 of about 4,080,709 (367)

Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.
This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario   +2 more
wiley   +1 more source

Thermally Drawn Shape and Stiffness Programmable Fibers for Medical Devices

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
Thermal drawing technique is adapted to fabricate Shape Memory Polymer Fibers (SMPFs) with programmable stiffness and shape. Multilumen and multimaterial SMPFs are developed for innovative medical devices: stiffness adjustable catheters, body temperature softening neural interfaces, and shape programmable cochlear implants.
Jiwoo Choi   +16 more
wiley   +1 more source

Liraglutide and Renal Outcomes in Type 2 Diabetes

open access: yesNew England Journal of Medicine, 2017
J. Mann   +8 more
semanticscholar   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo   +11 more
wiley   +1 more source

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