Results 41 to 50 of about 1,891,933 (319)

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

H2O2 generated by NADPH oxidase 4 contributes to transient receptor potential vanilloid 1 channel-mediated mechanosensation in the rat kidney [PDF]

, 2017
The presence of NADPH oxidase (Nox) in the kidney, especially Nox4, results in H2O2 production, which regulates Na+ excretion and urine formation.
Lin, Chian-Shiung;Lee, Shang-Hsing;Huang, Ho-Shiang;Chen, Yih-Sharng;Ma, Ming-Chieh, 陳益祥   +1 more
core   +1 more source

Preoperative inflammatory biomarkers reveal renal involvement in postsurgical mortality in hip fracture patients: an exploratory study

Frontiers in Immunology
BackgroundHip fractures in frail patients result in excess mortality not accounted for by age or comorbidities. The mechanisms behind the high risk of mortality remain undetermined but are hypothesized to be related to the inflammatory status of frail ...
Ana M. Valdes, Ana M. Valdes, Adeel Ikram, Adeel Ikram, Lauren A. Taylor, Lauren A. Taylor, Amy Zheng, Amy Zheng, Afroditi Kouraki, Afroditi Kouraki, Anthony Kelly, Anthony Kelly, Waheed Ashraf, Waheed Ashraf, Amrita Vijay, Amrita Vijay, Suzanne Miller, Suzanne Miller, Jessica Nightingale, Jessica Nightingale, Nicholas M. Selby, Benjamin J. Ollivere, Benjamin J. Ollivere   +22 more
doaj   +1 more source

The renal pentad

Indian Journal of Endocrinology and Metabolism, 2018
Diabetes management is a comprehensive exercise which encompasses not only glycemic control, but vascular risk reduction as well. Accepted clinical models such as the glycemic pentad and metabolic pentad list the glucose related and metabolic aspects which influence ling term vascular outcomes.
Sanjay Kalra, Manisha Sahay, Dinesh Dhanda, Rakesh Sahay   +3 more
openaire   +3 more sources

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]

, 2004
Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Anders, Hans-Joachim, Vielhauer, Volker, Eis, Vaclav, Schlöndorff, Detlef   +3 more
core   +1 more source

Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury

Frontiers in Immunology, 2019
Acute kidney injury (AKI) can be fatal and is a well-defined risk factor for the development of chronic kidney disease. Group 2 innate lymphoid cells (ILC2s) are innate producers of type-2 cytokines and are critical regulators of homeostasis in ...
Guy J. M. Cameron, Guy J. M. Cameron, Kelly M. Cautivo, Svenja Loering, Svenja Loering, Simon H. Jiang, Simon H. Jiang, Aniruddh V. Deshpande, Aniruddh V. Deshpande, Aniruddh V. Deshpande, Paul S. Foster, Paul S. Foster, Andrew N. J. McKenzie, Ari B. Molofsky, Philip M. Hansbro, Philip M. Hansbro, Philip M. Hansbro, Philip M. Hansbro, Malcolm R. Starkey, Malcolm R. Starkey   +19 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Who speaks for whom? Can nurses be patient advocates in renal settings? [PDF]

, 2014
Nursing texts laud the role of nurses as advocates for patients. With increased acknowledgement of patient-centred care, is it appropriate or desired for nurses to presume this as their role?
Wellard, Sally
core   +1 more source

New advances in assessment of the individual renal function in chronic unilateral renal obstruction using functional CT compared to 99mTc-DTPA renal scan [PDF]

, 2014
BACKGROUND: The selection of optimal treatment for obstructive nephrouropathy requires information about the functional status of each kidney. Nuclear renal scanning objectively measure differential renal function.
Hamed, Maged Abd Elgalil; Lecturer of Radiology and Nuclear Medicine, Zagazig University, Egypt
core   +2 more sources