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Analysis of gut microbiota and fecal/plasma short-chain fatty acids in non-dialysis renal anemia patients: associations with clinical parameters [PDF]

Frontiers in Microbiology
Renal anemia is one of the most common complications of chronic kidney disease (CKD). This study investigated gut microbiota composition and fecal/plasma short-chain fatty acids (SCFAs) in 30 non-dialysis renal anemia patients and 20 healthy controls ...
Lin Yang, Lifen Liu, Pingping Kong, Wenwen Xu, Zhiyuan Wang, Siqi He, Jing Lou, Yanna Dou   +7 more
doaj   +2 more sources

Eryptosis in renal anemia: mechanisms, clinical implications, and therapeutic targeting [PDF]

Frontiers in Pharmacology
Renal anemia is one of the most common complications of chronic kidney disease (CKD) and is associated with serious clinical consequences. Its prevalence increases significantly as renal function declines, affecting over 90% of dialysis patients ...
Xiang Deng, Xiang Deng, Xiangyu Gong, Yi Huang, Yi Huang, Jie Zhou, Jie Zhou, Sichong Ren, Sichong Ren, Sichong Ren   +9 more
doaj   +2 more sources

The Piezo1 hypothesis of renal anemia [PDF]

FASEB BioAdvances, 2022
AbstractErythropoietin deficiency is an extensively researched cause of renal anemia. The etiology and consequences of shortened red blood cell (RBC) life span in chronic kidney disease (CKD) are less well understood. Traversing capillaries requires RBC geometry changes, a process enabled by adaptions of the cytoskeleton.
Peter Kotanko, David J. Jörg, Nadja Grobe, Christoph Zaba   +3 more
openaire   +4 more sources

Conventional and complementary alternative medicine therapies for renal anemia: a literature review [PDF]

Frontiers in Endocrinology
Renal anemia stems mainly from chronic inflammation with elevated hepcidin levels, iron deficiency, and reduced red blood cell lifespan. Inadequate erythropoietin (EPO) production, worsened kidney function, leads to symptoms such as low energy, fatigue ...
Ching-Ming Lu, Ching-Ming Lu, Yuan-Hsuan Hsu, Yuan-Hsuan Hsu, I-Hsin Lin, Ko-Lin Kuo, Jian-Fu Liao, Hui-Fen Huang, Hui-Fen Huang, Ping-Hsun Lu, Ping-Hsun Lu   +10 more
doaj   +2 more sources

Attribute based cross classification analyses from the BRIGHTEN study reveal that therapeutic responsiveness to erythropoiesis stimulating agents predicts cardiorenal prognosis in renal anemia [PDF]

Scientific Reports
Renal anemia outcomes are influenced by sex and age; however, current guidelines for renal anemia lack sex- or age-specific standards for initiating treatment.
Hiroshi Kataoka, Terumasa Hayashi, Masaomi Nangaku, Ichiei Narita, Tatsuo Kagimura, Kosaku Nitta, Junichi Hoshino   +6 more
doaj   +2 more sources

Research progress on treatment of renal anemia in patients with chronic kidney disease [PDF]

Xin yixue, 2023
Renal anemia is a prevalent complication of chronic kidney disease （CKD）， which severely affects the prognosis of patients. The pathogenesis of renal anemia is complicated， and the core of which is erythropoietin deficiency and iron metabolism disorder ...
Li Yudong, Liao Wenjian, Luo Yonghang, Chen Qiuyu, Su Yong
doaj   +1 more source

Clinical features of anemia in membranous nephropathy patients: a Chinese cohort study

Renal Failure, 2023
Background Anemia is a common complication in patients with progressive chronic kidney disease. This cohort study evaluated the prevalence, clinical features and prognosis of membranous nephropathy (MN) with anemia.Methods We retrospectively analyzed a ...
Zhe Li, Weibo Le, Haitao Zhang, Dacheng Chen, Wencui Chen, Shuhua Zhu, Ke Zuo   +6 more
doaj   +1 more source

Renal Adaptation to Anemia [PDF]

Circulation Research, 1968
Renal adaptation to anemia was studied in dogs that had been bled repeatedly during a week to produce hematocrit values of between 12 and 21%. Total renal blood flow was unaltered despite a significant increase in cardiac output. Total renal oxygen consumption was within normal limits, but the Po 2 of cortical ...
A C, Aperia, A A, Liebow, L E, Roberts
openaire   +2 more sources

Importance of assessing biomarkers and physiological parameters of anemia-induced tissue hypoxia in the perioperative period

Brazilian Journal of Anesthesiology, 2023
Anemia is associated with increased risk of Acute Kidney Injury (AKI), stroke and mortality in perioperative patients. We sought to understand the mechanism(s) by assessing the integrative physiological responses to anemia (kidney, brain), the degrees of
Kyle Chin, Hannah Joo, Helen Jiang, Chloe Lin, Iryna Savinova, Sarah Joo, Ahmad Alli, Michael C. Sklar, Fabio Papa, Jeremy Simpson, Andrew J. Baker, C. David Mazer, William Darrah, Gregory M.T. Hare   +13 more
doaj   +1 more source

Effects of post-renal anemia treatment with the HIF-PHD inhibitor molidustat on adenine-induced renal anemia and kidney disease in mice

Journal of Pharmacological Sciences, 2020
The kidneys are the major organs for erythropoietin (EPO) production in adults, and thus, kidney damage results in reduced EPO levels and anemia. Inhibitors of Hypoxia-inducible factor-prolyl hydroxylase domain-containing protein (HIF-PHD) are awaited as
Lei Li, Daisuke Nakano, Anqi Zhang, Wararat Kittikulsuth, Norihiko Morisawa, Hiroyuki Ohsaki, Norio Suzuki, Masayuki Yamamoto, Akira Nishiyama   +8 more
doaj   +1 more source