Results 21 to 30 of about 889,891 (289)

Single-dose pharmacokinetics of recombinant human erythropoietin in patients with various degrees of renal failure [PDF]

, 1989
The pharmacokinetic profile of recombinant human erythropoietin (rHuEpo) was studied after a single intravenous dose of 150 U/kg in ten patients with various degrees of renal function: group I, creatinine clearance greater than 80 ml/min, n = 2; group II,
K. Jandeleit, Eckardt, K. U., A. Kurtz, B. Ehmer, A. Schreiber, Sieberth, H. G., Kindler, J., Jandeleit, K., Schreiber, A., Ehmer, B., Kurtz, Armin, Sieberth, H.-G., K.-U. Eckardt, Kurtz, A., H.-G. Sieberth, P. Scigalla, Scigalla, P., Eckardt, Kai-Uwe, J. Kindler   +18 more
core   +1 more source

Epidemiology and outcomes in patients with anemia of CKD not on dialysis from a large US healthcare system database: a retrospective observational study

BMC Nephrology, 2022
Background Optimal management of anemia of chronic kidney disease (CKD) remains controversial. This retrospective study aimed to describe the epidemiology and selected clinical outcomes of anemia in patients with CKD in the US.
Lois Lamerato, Glen James, Heleen van Haalen, Katarina Hedman, James A. Sloand, Amy Tang, Eric T. Wittbrodt, Jerry Yee   +7 more
doaj   +1 more source

What should be responsible for eryptosis in chronic kidney disease?

Kidney & Blood Pressure Research, 2022
Background: Renal anemia is an important complication of chronic kidney disease (CKD). In addition to insufficient secretion of erythropoietin (EPO) and erythropoiesis disorders, the impact of eryptosis on renal anemia demands attention.
Dongxin Li, Xujuan Zheng, Yunxia Zhang, Xiangling Li, Xuexun Chen, Yonghua Yin, Jingwen Hu, Jialin Li, Min Guo, Xiangming Wang   +9 more
doaj   +1 more source

Research advances on the mechanism of gut microbiota in renal anemia

Linchuang shenzangbing zazhi, 2022
Renal anemia is a common complication of chronic kidney disease （CKD）. Human gut microbiota participates in human metabolism， immunity and other functions， playing vital roles in the regulation of human health. Numerous studies have demonstrated that any
Shi-jin Liu, Jia Song, Zun-song Wang
doaj  

Increased plasma viscosity as a reason for inappropriate erythropoietin formation [PDF]

, 1993
The aim of this study was to examine whether altered plasma viscosity could contribute to the inappropriately low production rate of erythropoietin (EPO) observed in patients suffering from hypergammaglobulinemias associated with multiple myeloma or ...
A Zimmermann, K H Götz, Ratcliffe, P. J., Ratcliffe, Peter, Reinhart, WH, Götz, Karlheinz, Hamann, M., Götz, KH, M Hamann, A Kurtz, A Singh, Kurtz, A, Reinhart, W. H., Singh, A., Zimmermann, A., Kurtz, Armin, K U Eckardt, Hamann, M, Singh, A, Eckardt, KU, P J Ratcliffe, W H Reinhart, Zimmermann, A, Eckardt, Kai-Uwe   +23 more
core   +1 more source

Pathophysiology of anemia in chronic kidney diseases: A review

Biomedical Papers, 2015
Backgroud. Anemia is one of the laboratory and clinical findings of chronic kidney diseases (CKD). The presence of anemia in patients with CKD has a wide range of clinically important consequences.
Josef Zadrazil, Pavel Horak
doaj   +1 more source

Role of excretory graft function for erythropoietin formation after renal transplantation [PDF]

, 1990
To examine the role of renal excretory function for erythropoietin (EPO) formation we have determined the kinetics of plasma immunoreactive EPO (irEPO) in patients with end-stage renal disease undergoing renal allotransplantation (RTX).
V. KLIEM, U. FREI, Bauer, Christian, C. BAUER, V. KLIEM, Koch, K. M., K. M. KOCH, Kurtz, Armin, Frei, U., A. KURTZ, Kliem, V., Eckardt, Kai-Uwe, K.‐U. ECKARDT, K.-U. ECKARDT   +13 more
core   +1 more source

Cardio-renal-anemia syndrome: A report of three cases

Saudi Journal of Kidney Diseases and Transplantation, 2012
Patients with chronic kidney diseases (CKDs) and cardiovascular diseases (CVDs) present with various degree of anemia. Anemia has been associated with poor outcome in patients with CKD and CVD.
U H Okafor, E I Unuigbe
doaj   +1 more source

Associations between renal impairment and anemia in older, rural Japanese men: the Nagasaki Island study [PDF]

, 2014
Background: Renal impairment is known to be associated with atherosclerosis, which in turn is reported to be positively associated with hemoglobin levels. In addition, renal impairment is known to be associated with a form of anemia known as renal anemia.
Tamai, Mami, Yamasaki, Hironori, Maeda, Takahiro, Nagayoshi, Mako, Arima, Kazuhiko, Kusano, Yosuke, Yamanashi, Hirotomo, Sato, Shimpei, Koyamatsu, Jun, Kadota, Koichiro, Takamura, Noboru, Shimizu, Yuji   +11 more
core   +1 more source

Impact of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor on Renal Function in Patient with Heart Failure

Journal of Cardiovascular Development and Disease, 2021
Hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor is a recently introduced oral agent to treat renal anemia, but its clinical implications on renal functioning in patients with heart failure remains unknown.
Teruhiko Imamura, Yohei Ueno, Koichiro Kinugawa   +2 more
doaj   +1 more source