Results 61 to 70 of about 889,891 (289)

Anemia Prevalence among Pregnant Women and Birth Weight in Five Areas in China [PDF]

, 2009
Objectives: To investigate the current prevalence of anemia among pregnant women in different areas of China and the association with birth weight and educational level.
R.X. Xu, Sun, Y.Y., Y.Y. Sun, Li, Y., Q.Z. Wang, Zheng, M.C., Wang, Q.Z., M.C. Zheng, E. Schouten, Ma, A.G., A.G. Ma, Y. Li, Schouten, E.G., Wang, Y., Y. Wang, Xu, R.X.   +15 more
core   +1 more source

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

Anemia in Children With Chronic Renal Failure

Turkish Journal of Nephrology, 2019
Anemia is a common finding in children with chronic renal failure (CRF) due to the decreased production of erythropoietin when glomerular filtration rate diminishes below 35 mL/min/1.73m2.
Harika ALPAY, Neşe KARAASLAN BIYIKLI
doaj  

Context‐Dependent Inverse Association of Glucose–Lipid Metabolic Status With Anemia: Evidence From Multinational Multicohort Analyses

Advanced Science, EarlyView.
Across six multinational cohorts, higher triglyceride–glucose index values are consistently associated with lower prevalent and incident anemia, despite their established adverse cardiometabolic significance. This inverse relationship varies across inflammatory, cardiovascular, and renal contexts, suggesting that glucose–lipid metabolic status carries ...
Guosong Jiang, Xinxing Wang, Lianfeng Xie, Wenna Ding, Yingyong Yin, Mei Yao, Zhibo Cui, Kaiqiang Tang, Lijie Zhong, Zhi Wang, Jia Wang, Lei Lei, Xiaoxiao Qu, Chi‐E. Qiu   +13 more
wiley   +1 more source

Renal anemia: from erythropoietin deficiency to erythropoietin resistance

Frontiers in Pharmacology
Renal anemia is one of the core complications of chronic kidney disease (CKD) and is closely associated with poor patient prognosis. Renal interstitial fibrosis or impaired oxygen sensing leads to insufficient erythropoietin (EPO) production, which ...
Aojiao Chu, Jinyang Bu, Xinfu Zou, Zheng Zhang, Qin Zheng, Ling Shi, Meihong Luo   +6 more
doaj   +1 more source

Microalbuminuria as Predictor of Early Glomerular Injury in Children and Adolescents with Sickle Cell Anaemia at Muhimbili National Hospital Dar es Salaam, Tanzania 2012 [PDF]

, 2012
Microalbuminuria (MA) is the earliest marker of various diseases affecting the renal system. Its relevance in children and adolescents with sickle cell anaemia (SCA), who are known to be prone to renal complications, has not been fully explored in our ...
Christopher, Richard, Christopher, R.
core  

Role of erythropoietin in renal anemia therapy [PDF]

, 2016
Renal anemia is a common complication of chronic renal failure caused by erythropoietin deficiency; targeting erythropoietin is a common approach to renal anemia treatment.
Xing, Xuekun, Sun, Huishan, Zhang, Wenbo
core   +1 more source

Alkylating Agent–Induced FANCL Impairment Damages Pulmonary Arterial, Venous, and Microvascular Endothelial Cells and Predisposes to PAH/PVOD

Advanced Science, EarlyView.
This study establishes a novel cisplatin‐induced rat model of PAH/PVOD and identifies a conserved mechanistic axis—FANCL impairment, DNA damage accumulation, and endothelial dysfunction—triggered by cisplatin or mitomycin C across pulmonary arteries, veins, and microvessels.
Shiyun Liu, Yufei Sun, Xinlei Wu, Haixia Chen, Shaocong Mo, Zichong Li, Yiwei Gong, Xiaoqian Shan, Yuanqi Li, Yaru Guan, Junqi Zhu, Han Yan, Min Du, Feng Wei, Peixin Ou, Ziyi Wang, Chenting Zhang, Lei Xu, Wenju Lu, Jian Wang, Kai Yang   +20 more
wiley   +1 more source

Prevalence of anemia in type 2 diabetes and role of renal involvement

Saudi Journal of Kidney Diseases and Transplantation, 2011
Anemia is more common and more severe in diabetics compared to nondiabetic chronic kidney disease patients. This study was undertaken to determine the prevalence of anemia and the contribution of level of nephropathy to anemia in type 2 diabetic patients.
Shokoufeh Bonakdaran, Mohammad Gharebaghi, Mohammad Vahedian   +2 more
doaj  

Renal erythropoietin-producing cells in health and disease

Frontiers in Physiology, 2015
Erythropoietin (Epo) is an indispensable erythropoietic hormone primarily produced from renal Epo-producing cells (REPs). Epo production in REPs is tightly regulated in a hypoxia-inducible manner to maintain tissue oxygen homeostasis.
Tomokazu eSouma, Tomokazu eSouma, Tomokazu eSouma, Norio eSuzuki, Masayuki eYamamoto   +4 more
doaj   +1 more source