Results 81 to 90 of about 889,891 (289)

Management of bilateral idiopathic renal hematuria in a dog with silver nitrate [PDF]

, 2013
Renal hematuria has limited treatment options. This report describes management of bilateral idiopathic renal hematuria in a dog with surgically assisted installation of 0.5% silver nitrate solution.
Di Cicco, Michael F, Jermyn, Kieri, Hill, Tracy, Secoura, Patricia L, Fetzer, Tara, Vaden, Shelly, Chaloub, Serge   +6 more
core  

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Disfunção renal e anemia em pacientes com insuficiência cardíaca com fração de ejeção reduzida versus normal Renal dysfunction and anemia in patients with heart failure with reduced versus normal ejection fraction

Arquivos Brasileiros de Cardiologia, 2010
FUNDAMENTO: A presença de anemia e de disfunção renal confere mau prognóstico em pacientes com insuficiência cardíaca (IC) e fração de ejeção reduzida (ICFER). O impacto em pacientes com IC e fração de ejeção normal (ICFEN) é pouco estudado.
Humberto Villacorta, Bolivar F. Saenz-Tello, Eduarda Barcellos dos Santos, Ricardo Steffen, Christiane Wiefels, Luiz Costa Lima, Ana Luíza F. Sales, Pedro Soares, Evandro Tinoco Mesquita   +8 more
doaj   +1 more source

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source

Nutritional status, hospitalization and mortality among patients with sickle cell anemia in Tanzania. [PDF]

, 2011
BACKGROUND: Reduced growth is common in children with sickle cell anemia, but few data exist on associations with long-term clinical course. Our objective was to determine the prevalence of malnutrition at enrollment into a hospital-based cohort and ...
Soka, Deogratius, Prentice, AM, Komba, Albert N, Prentice, Andrew M, C. R. Newton, A. M. Prentice, Komba, AN, Williams, TN, Fulford, AJ, Makani, J, Newton, Charles R, S. E. Cox, D. Soka, Newton, CR, A. N. Komba, Soka, D, Marsh, K, Cox, SE, Fulford, Anthony J, K. Marsh, Williams, Thomas N, J. Makani, Cox, Sharon E, Williams, Thomas, Makani, Julie, Marsh, Kevin, T. N. Williams, A. J. Fulford   +27 more
core   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

Mending the Valve, Burdening the Kidney: A Case of Renal Hemosiderosis With Mitral Valve Repair

Case Reports in Nephrology
Renal hemosiderosis, marked by the buildup of hemosiderin in the renal cortex due to chronic intravascular hemolysis, can lead to acute kidney injury. Iron deposited may exacerbate renal damage through processes like lipid peroxidation and free radical ...
Sadikshya Bhandari, Tenzin Tamdin, Raymond Raut   +2 more
doaj   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Emerging Therapies for Anemia in Chronic Kidney Disease: An Updated Review

Haematology Journal of Bangladesh
Anemia is a common and significant consequence of chronic kidney disease (CKD), affecting quality of life, cardiovascular events, hospitalization rates and mortality.
A.K.M Shahidur Rahman, Md. Masudul Karim
doaj   +1 more source