Results 91 to 100 of about 324,151 (312)

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Management of bilateral idiopathic renal hematuria in a dog with silver nitrate

, 2013
Renal hematuria has limited treatment options. This report describes management of bilateral idiopathic renal hematuria in a dog with surgically assisted installation of 0.5% silver nitrate solution.
Di Cicco, Michael F, Jermyn, Kieri, Hill, Tracy, Secoura, Patricia L, Fetzer, Tara, Vaden, Shelly, Chaloub, Serge   +6 more
core  

Myogenic constriction in renal failure : cause and therapy [PDF]

, 2012
In bloeddruk regulerende vaten, de zogenaamde weerstandsvaten, wordt myogene constrictie geactiveerd door verhoogde transmurale druk. De verhoogde transmurale druk zorgt voor contractie van het arteriële gladde spierweefsel, met vernauwing van het lumen ...
Vavrinec, Peter,, Vavrinec, Peter
core  

Idiopathic Spontaneous Renal Artery Dissection: A Rare Case

Turkish Journal of Nephrology, 2019
Spontaneous renal artery dissection is a rare and serious event that can result in renal parenchymal injury and severe hypertension. We report a case of a 38-year-old previously healthy man who presented with unilateral flank pain and had a renal artery ...
Yeter BAYRAM, Faruk TURGUT, İsmail KIRBAŞ, Mehmet KANBAY   +3 more
doaj  

Use of fenestrated-branched endovascular aneurysm repair to treat Carrel patch aneurysmal degeneration after open thoracoabdominal aortic aneurysm repair

Journal of Vascular Surgery Cases and Innovative Techniques, 2019
Two patients with a history of open type II thoracoabdominal aortic aneurysm repair presented with saccular aneurysmal degeneration of the Carrel patch.
Tammy T. Nguyen, MD, PhD, Jessica P. Simons, MD, MPH, Andres Schanzer, MD   +2 more
doaj   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

[Hypertension therapy in patients with renal artery stenosis]

, 2012
Renovascular hypertension is due to reduced renal parenchymal perfusion. The correct diagnosis can be difficult. It is important to note that the demonstration of renal artery stenosis in a patient with hypertension does not necessarily constitute ...
Maillard, Maillard, Burnier, Michel, Vogt, Bruno   +2 more
core  

Unique Case of Entwined Left Testicular and Left Renal Artery Forming an Arterial Arch Over the Left Renal Vein

Online Journal of Health & Allied Sciences, 2017
Testicular arteries are the main arteries supplying the testis. An anatomical variation in the course of the left testicular artery and left renal artery is presented in this case report, highlighting its clinical implications. The left testicular artery
Ashwini Aithal P, Naveen Kumar, Swamy Ravindra S, Gayathri S Prabhu   +3 more
doaj  

Blood Pressure Response to Main Renal Artery and Combined Main Renal Artery Plus Branch Renal Denervation in Patients With Resistant Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundSingle‐electrode ablation of the main renal artery for renal sympathetic denervation showed mixed blood pressure (BP)‐lowering effects. Further improvement of the technique seems crucial to optimize effectiveness of the procedure.
Karl Fengler, Sebastian Ewen, Robert Höllriegel, Karl‐Philipp Rommel, Saaraaken Kulenthiran, Lucas Lauder, Bodo Cremers, Gerhard Schuler, Axel Linke, Michael Böhm, Felix Mahfoud, Philipp Lurz   +11 more
doaj   +1 more source

Renal Artery Dissection

Annals of Surgery, 1984
Renal artery dissections are stenotic or occlusive lesions most often observed in hypertensive patients with underlying atherosclerosis or fibromuscular disease. Acute dissections may present spontaneously, as a complication of diagnostic or therapeutic angiography or as an agonal event associated with overwhelming systemic illness. Chronic dissections
B M, Smith, G W, Holcomb, R E, Richie, R H, Dean   +3 more
openaire   +3 more sources