Results 101 to 110 of about 492,176 (360)

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

Use of fenestrated-branched endovascular aneurysm repair to treat Carrel patch aneurysmal degeneration after open thoracoabdominal aortic aneurysm repair

open access: yesJournal of Vascular Surgery Cases and Innovative Techniques, 2019
Two patients with a history of open type II thoracoabdominal aortic aneurysm repair presented with saccular aneurysmal degeneration of the Carrel patch.
Tammy T. Nguyen, MD, PhD   +2 more
doaj   +1 more source

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

open access: yesAdvanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu   +12 more
wiley   +1 more source

Idiopathic Spontaneous Renal Artery Dissection: A Rare Case

open access: yesTurkish Journal of Nephrology, 2019
Spontaneous renal artery dissection is a rare and serious event that can result in renal parenchymal injury and severe hypertension. We report a case of a 38-year-old previously healthy man who presented with unilateral flank pain and had a renal artery ...
Yeter BAYRAM   +3 more
doaj  

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu   +15 more
wiley   +1 more source

Risk factor analysis for fast track protocol failure [PDF]

open access: yes, 2013
Background: The introduction of fast-track treatment procedures following cardiac surgery has significantly shortened hospitalisation times in intensive care units (ICU).
Bingold, Tobias Michael   +5 more
core   +1 more source

Neutrophil‐Driven Cascade‐Targeted Nanocarriers Restore Mitochondrial Homeostasis to Ameliorate Renal Ischemia–Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
A neutrophil‐mediated dual‐targeting liposome (NKN‐LNP) is developed to treat renal ischemia–reperfusion injury. The system enables spatiotemporally controlled delivery of NMN to injured tubules via MMP‐2/9 activation and KIM1 recognition, restoring mitochondrial function through NAD+‐SIRT3 signaling and preventing the transition from acute kidney ...
Hangbin Ma   +15 more
wiley   +1 more source

Novel Vascular‐Adaptive Liquid Metal Microspheres Enable Visualized Arterial Embolization Therapy

open access: yesAdvanced Science, EarlyView.
We present drug‐loaded liquid metal microspheres (X‐MEN) as a novel agent for image‐guided arterial embolization. With inherent radiopacity and superior deformability, X‐MEN enables real‐time monitoring and conforms tightly to irregular vessels. This approach ensures precise, long‐lasting embolization without recanalization, addressing critical ...
Chenyu Shen   +14 more
wiley   +1 more source

Combined Renal Artery Stenosis and Renal Artery Aneurysm As a Cause of Renovascular Hypertension: A Case Report

open access: yesTurkish Journal of Nephrology, 2019
Over the last decade there has been an increased awareness of renovascular disease as a potentially correctable cause of hypertension and renal insufficiency. Renal artery stenosis is most commonly due to either atherosclerosis or fibromuscular dysplasia.
İhsan ERGÜN   +6 more
doaj   +2 more sources

Changes of Renal Blood Flow Following Various Renal Denervation Procedures in Intact Kidneys of Rabbits Using Colored Microspheres [PDF]

open access: yes, 2002
 We investigated effects of acute renal denervation procedures on renal hemodynamics in intact kidneys of rabbits. Fifty-one Japanese white male rabbits were used. Renal blood flow (RBF) was measured by colored microspheres.
三浦 洋靖   +3 more
core  

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