Results 101 to 110 of about 324,151 (312)

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

A new surgical approach for exclusion of renal artery aneurysms avoiding organ ischemia

, 2008
INTRODUCTION: Surgical treatment of renal artery aneurysms is inevitably associated with temporary renal artery occlusion and risk of ischemic injury.
Demertzis, S, Trunfio, R., Demertzis, S., Siclari, F., Siclari, F, Trunfio, R, van den Berg, J C, van den Berg, J.C.   +7 more
core   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

Renal artery stenosis: epidemiology and treatment

, 2014
Benjamin R Weber, Robert S DieterLoyola University Medical Center, Maywood, IL, USAAbstract: Renal artery stenosis (RAS) is a frequently encountered problem in clinical practice.
Dieter RS, Weber BR
core  

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

Advanced Science, EarlyView.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian, Yanrui Yang, Qiuyu Li, Ying Hu, Qin Hu, Shasha Ran, Siyu Zhou, Xiujuan Yang, Shanshan Li, Qixiong Zhang   +9 more
wiley   +1 more source

Ex vivo renal artery reconstruction for complex renal artery disease

, 2014
ObjectiveThe objective of this study was to evaluate long-term outcome of renal revascularization by ex vivo renal artery reconstruction for complex renal artery disease.MethodsFrom 1987 to 2012, 23 patients (17 women; mean age, 45 years) with complex ...
Weaver, Fred A., Ham, Sung Wan
core   +1 more source

Combined Renal Artery Stenosis and Renal Artery Aneurysm As a Cause of Renovascular Hypertension: A Case Report

Turkish Journal of Nephrology, 2019
Over the last decade there has been an increased awareness of renovascular disease as a potentially correctable cause of hypertension and renal insufficiency. Renal artery stenosis is most commonly due to either atherosclerosis or fibromuscular dysplasia.
İhsan ERGÜN, Şule Şengül, Yakup EKMEKÇİ, Sim KUTLAY, Tanzer SANCAK, Neval DUMAN, Bülent ERBAY   +6 more
doaj   +2 more sources

Enhancing Blood Circulation With Epsilon‐Near‐Zero (ENZ) Materials via the Far‐Infrared Window of Human Skin

Advanced Science, EarlyView.
Epsilon‐near‐zero (ENZ) silicon carbide enables a selective far‐infrared emitter spectrally aligned with the human skin window around 10 µm for wavelength‐matched thermal therapy. In 25 within‐subject trials (50 hands) monitored by laser speckle contrast imaging, SiC increases blood perfusion by 30.2% versus a broadband graphite emitter while ...
Wen‐Teng Yao, Shan‐Chiao Yang, Ming‐Feng Tsai, Hsuen‐Li Chen   +3 more
wiley   +1 more source

Diagnosis and surgical treatment of renal artery aneurysms

Acta Medica Leopoliensia, 2019
Aim. Improvement of diagnosis and surgical treatment of renal artery aneurysms.  Material and Methods. The features of the clinical course, diagnosis and surgical treatment of renal artery aneurysm were analyzed in a 55-year-old patient.
I.I. Kobza, T.I. Kobza, Yu.S. Mota
doaj   +1 more source