Results 101 to 110 of about 307,107 (314)

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

open access: yesAdvanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang   +7 more
wiley   +1 more source

Outcomes after stenting of renal artery stenosis in patients with high-risk clinical features

open access: yesThe Egyptian Heart Journal
Background In patients with renal artery stenosis, revascularization was seen as a mean to improve outcomes, but large studies failed to show significant benefit in general population.
Calin Homorodean   +10 more
doaj   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li   +9 more
wiley   +1 more source

REMOVAL OF THE CLIP ON THE RENAL ARTERY IN RABBITS WITH EXPERIMENTAL CHRONIC HYPERTENSION [PDF]

open access: bronze, 1954
P. M. Daniel   +2 more
openalex   +1 more source

Quantitative Stain Mapping in X‐Ray Virtual Histology

open access: yesAdvanced Science, EarlyView.
Virtual histology promises 3D tissue examination without physical sectioning, yet has lacked the tissue‐specificity of conventional pathology. This work demonstrates the first quantitative three‐dimensional stain mapping at histologically relevant resolution, separating contrast agent from tissue to reveal cellular features such as nuclei. The approach
Dominik John   +16 more
wiley   +1 more source

Favorable outcomes with in situ techniques for surgical repair of complex renal artery aneurysms [PDF]

open access: bronze, 2010
William P. Robinson   +3 more
openalex   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

open access: yesAdvanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin   +18 more
wiley   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li   +7 more
wiley   +1 more source

Assessment of ultrasound criteria for high-grade renal artery stenosis in transplant kidneys

open access: yesJVS-Vascular Insights
Objective: Renal artery stenosis is an uncommon vascular complication following kidney transplantation. Noninvasive renal artery duplex is frequently used for initial screening.
Melissa D’Andrea, MD   +5 more
doaj   +1 more source

Neurofibromatosis and renal artery stenosis: A case of familial incidence [PDF]

open access: bronze, 1988
Garnet R. Craddock   +2 more
openalex   +1 more source

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