Renal blood flow and oxygenation. [PDF]
Pflugers Arch, 2022 Our kidneys receive about one-fifth of the cardiac output at rest and have a low oxygen extraction ratio, but may sustain, under some conditions, hypoxic injuries that might lead to chronic kidney disease.
Edwards A, Kurtcuoglu V.
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Renal pericytes: regulators of medullary blood flow [PDF]
Acta Physiologica, 2012 Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Agmon Y. +27 more
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Molecular mechanisms of renal blood flow autoregulation. [PDF]
Curr Vasc Pharmacol, 2014 Diabetes and hypertension are the leading causes of chronic kidney disease and their incidence is increasing at an alarming rate. Both are associated with impairments in the autoregulation of renal blood flow (RBF) and greater transmission of fluctuations in arterial pressure to the glomerular capillaries.
Burke M, Pabbidi MR, Farley J, Roman RJ.
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Pericyte-mediated constriction of renal capillaries evokes no-reflow and kidney injury following ischaemia [PDF]
eLife, 2022 Acute kidney injury is common, with ~13 million cases and 1.7 million deaths/year worldwide. A major cause is renal ischaemia, typically following cardiac surgery, renal transplant or severe haemorrhage.
Felipe Freitas, David Attwell
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Renal blood flow in sepsis [PDF]
Critical Care, 2005 INTRODUCTION: To assess changes in renal blood flow (RBF) in human and experimental sepsis, and to identify determinants of RBF. METHOD: Using specific search terms we systematically interrogated two electronic reference libraries to identify ...
Bellomo, Rinaldo +5 more
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TRPV1 protects renal ischemia-reperfusion injury in diet-induced obese mice by enhancing CGRP release and increasing renal blood flow [PDF]
PeerJ, 2019 Background Obesity is a major risk factor for end-stage renal disease. Using transient receptor potential vanilloid 1 knockout (TRPV1−/−) mice, we tested the hypothesis that TRPV1 protects against obesity-induced exacerbation of renal ischemia ...
Beihua Zhong +2 more
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Electrically stimulated acupuncture increases renal blood flow through exosome-carried miR-181.
Am J Physiol Renal Physiol, 2018 Acupuncture with low-frequency electrical stimulation (Acu/LFES) can prevent muscle atrophy by increasing muscle protein anabolism in mouse models of chronic kidney disease.
Klein JD, Wang XH.
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Changes in Renal Blood Flow and Possibly the Intrarenal Distribution of Blood during the Natriuresis Accompanying Saline Loading in the Dog* [PDF]
Journal of Clinical Investigation, 1965 ing limb of Henle's loop, resulting in the delivery of a larger volume of fluid of lower sodium concentration to the transport sites of the ascending limb of the loop.
Laurence E. Earley, Robert M. Friedler
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Glomerular Filtration Rate, Renal Blood Flow and Blood Viscosity during and after Diabetic Coma [PDF]
Circulation Research, 1953 The azotemia of patients in diabetic coma is the result of impaired blood supply, unless tubular impairment antedates or supervenes. Clearance and blood pressure data are presented which strongly suggest that increased blood viscosity is the dominant ...
François C. Reubi
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The renal blood flow reserve in healthy humans and patients with atherosclerotic renovascular disease measured by positron emission tomography using [15O]H2O [PDF]
EJNMMI Research, 2018 Background Microvascular function plays an important role in ARVD (atherosclerotic renovascular disease). RFR (renal flow reserve), the capacity of renal vasculature to dilate, is known to reflect renal microvascular function.
Johanna Päivärinta +8 more
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