TRPV1 protects renal ischemia-reperfusion injury in diet-induced obese mice by enhancing CGRP release and increasing renal blood flow [PDF]
PeerJ, 2019 Background Obesity is a major risk factor for end-stage renal disease. Using transient receptor potential vanilloid 1 knockout (TRPV1−/−) mice, we tested the hypothesis that TRPV1 protects against obesity-induced exacerbation of renal ischemia ...
Beihua Zhong +2 more
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The renal blood flow reserve in healthy humans and patients with atherosclerotic renovascular disease measured by positron emission tomography using [15O]H2O [PDF]
EJNMMI Research, 2018 Background Microvascular function plays an important role in ARVD (atherosclerotic renovascular disease). RFR (renal flow reserve), the capacity of renal vasculature to dilate, is known to reflect renal microvascular function.
Johanna Päivärinta +8 more
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Comparison of Renal Blood Flow Using Maximum Slope-Based Computed Tomography Perfusion and Ultrasound Flow Probe in Healthy Dogs [PDF]
Frontiers in Veterinary Science, 2020 Computed tomography (CT) perfusion can analyze tissue perfusion and quantitative parameters, including blood flow, blood volume, and transit time. CT perfusion has been used for evaluating split renal function.
Sang-Kwon Lee +4 more
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Extracellular superoxide dismutase is necessary to maintain renal blood flow during sepsis development. [PDF]
Intensive Care Med Exp, 2017 Background: Extracellular superoxide dismutase (ECSOD) protects nitric oxide (NO) bioavailability by decreasing superoxide levels and preventing peroxynitrite generation, which is important in maintaining renal blood flow and in preventing acute kidney ...
Constantino L +12 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Abnormal renal hemodynamic responses to salt‐loading are thought to contribute to salt‐sensitive (SS) hypertension. However, this is based largely on studies in anesthetized animals, and little data are available in conscious SS and salt ...
Jacqueline C. Potter +10 more
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Simulation and Analyses of Turbulent Flow in Different Phases of Stenosed Renal Artery [PDF]
MATEC Web of Conferences, 2023 This study concerns the two-dimensional structure computational results of renal artery stenosis. In this paper, the turbulent flow of the stenosed vessel is stimulated and correlates the different stages of stenosis with each other.
Zia Zahra +4 more
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PHARMACOLOGICAL CORRECTION OF INTERCEPT HEMODYNAMICS IN ACUTE KIDNEY DAMAGE (PART 1) [PDF]
Research Results in Pharmacology, 2017 Introduction: Development of vasoconstriction of kidney arterioles and reduction of renal blood flow is one of the main mechanism of acute kidney injury (AKI) formation. Methods for evaluation of intrarenal hemodynamics status are rather limited. Evident
Katherine Shramenko +5 more
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eLife, 2022 Acute kidney injury is common, with ~13 million cases and 1.7 million deaths/year worldwide. A major cause is renal ischaemia, typically following cardiac surgery, renal transplant or severe haemorrhage.
Felipe Freitas, David Attwell
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Effects of Platelet-Rich Plasma (PRP) on a Model of Renal Ischemia-Reperfusion in Rats. [PDF]
PLoS ONE, 2016 Renal ischemia-reperfusion injury is a major cause of acute renal failure, causing renal cell death, a permanent decrease of renal blood flow, organ dysfunction and chronic kidney disease.
Oriol Martín-Solé +5 more
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THE ROLE OF L-TYPE CALCIUM CHANNELS IN THE MEDIATION OF FAST OSCILLATION OF ARTERIAL BLOOD PRESSURE AND RENAL BLOOD FLOW IN RATS [PDF]
Trakia Journal of Sciences, 2019 The investigation of dynamic characteristics of blood pressure and renal blood flow provides detailed information about the fast regulatory mechanisms involved in arterial blood pressure (ABP) and renal blood flow (RBF) autoregulation.
P. Markova, R. Girchev
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