Results 141 to 150 of about 571,370 (304)

Advances in Electrochemical Urea Biosensors: Trends and Future Prospects

open access: yesAdvanced Sensor Research, EarlyView.
This review explores advances in enzymatic and non‐enzymatic biosensors, emphasizing electrochemical detection, material innovations, and IoT integration for real‐time tracking. Key challenges and future opportunities in enhancing sensitivity, selectivity, and portability are highlighted, showcasing biosensors as promising tools for next‐generation ...
Samar Shurbaji   +6 more
wiley   +1 more source

Smoking effects on renal and central hemodynamics in men and women with essential arterial hypertension

open access: yesКардиоваскулярная терапия и профилактика, 2009
Aim. To compare renal and central hemodynamic parameters in smoking and non-smoking men and women with essential arterial hypertension (EAH).Material and methods.
V. I. Podzolkov   +2 more
doaj  

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

open access: yesAdvanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan   +13 more
wiley   +1 more source

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

open access: yesAdvanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang   +10 more
wiley   +1 more source

Assessing Renal Microvascular Reactivity by Laser Speckle-Contrast Imaging in Angiotensin-II-Treated Mice

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2020
Nicolas Mottard,1,2 Dan E Berkowitz,1,3 Lakshmi Santhanam1,3 1Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; 2Department of Anesthesiology and Critical Care, Clinique de la ...
Mottard N, Berkowitz DE, Santhanam L
doaj  

Inhibiting Liver‐Derived C3 Protein Rescues Anesthesia/Surgery‐Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis

open access: yesAdvanced Science, EarlyView.
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu   +17 more
wiley   +1 more source

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