TRPV1 protects renal ischemia-reperfusion injury in diet-induced obese mice by enhancing CGRP release and increasing renal blood flow. [PDF]
PeerJ, 2019 Background Obesity is a major risk factor for end-stage renal disease. Using transient receptor potential vanilloid 1 knockout (TRPV1−/−) mice, we tested the hypothesis that TRPV1 protects against obesity-induced exacerbation of renal ischemia ...
Zhong B, Ma S, Wang DH.
europepmc +3 more sources
The renal blood flow reserve in healthy humans and patients with atherosclerotic renovascular disease measured by positron emission tomography using [15O]H2O. [PDF]
EJNMMI Res, 2018 Background Microvascular function plays an important role in ARVD (atherosclerotic renovascular disease). RFR (renal flow reserve), the capacity of renal vasculature to dilate, is known to reflect renal microvascular function.
Päivärinta J +8 more
europepmc +2 more sources
Mathematical Model of Volume Kinetics and Renal Function after Burn Injury and Resuscitation [PDF]
Burns, 47(2), pp.371-386 (2021), 2021 This paper presents a mathematical model of blood volume kinetics and renal function in response to burn injury and resuscitation, which is applicable to the development and non-clinical testing of burn resuscitation protocols and algorithms. Prior mathematical models of burn injury and resuscitation are not ideally suited to such applications due to ...
arxiv +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Abnormal renal hemodynamic responses to salt‐loading are thought to contribute to salt‐sensitive (SS) hypertension. However, this is based largely on studies in anesthetized animals, and little data are available in conscious SS and salt ...
Jacqueline C. Potter +10 more
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Simulation and Analyses of Turbulent Flow in Different Phases of Stenosed Renal Artery [PDF]
MATEC Web of Conferences, 2023 This study concerns the two-dimensional structure computational results of renal artery stenosis. In this paper, the turbulent flow of the stenosed vessel is stimulated and correlates the different stages of stenosis with each other.
Zia Zahra +4 more
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PHARMACOLOGICAL CORRECTION OF INTERCEPT HEMODYNAMICS IN ACUTE KIDNEY DAMAGE (PART 1) [PDF]
Research Results in Pharmacology, 2017 Introduction: Development of vasoconstriction of kidney arterioles and reduction of renal blood flow is one of the main mechanism of acute kidney injury (AKI) formation. Methods for evaluation of intrarenal hemodynamics status are rather limited. Evident
Katherine Shramenko +5 more
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eLife, 2022 Acute kidney injury is common, with ~13 million cases and 1.7 million deaths/year worldwide. A major cause is renal ischaemia, typically following cardiac surgery, renal transplant or severe haemorrhage.
Felipe Freitas, David Attwell
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Effects of Platelet-Rich Plasma (PRP) on a Model of Renal Ischemia-Reperfusion in Rats. [PDF]
PLoS ONE, 2016 Renal ischemia-reperfusion injury is a major cause of acute renal failure, causing renal cell death, a permanent decrease of renal blood flow, organ dysfunction and chronic kidney disease.
Oriol Martín-Solé +5 more
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THE ROLE OF L-TYPE CALCIUM CHANNELS IN THE MEDIATION OF FAST OSCILLATION OF ARTERIAL BLOOD PRESSURE AND RENAL BLOOD FLOW IN RATS [PDF]
Trakia Journal of Sciences, 2019 The investigation of dynamic characteristics of blood pressure and renal blood flow provides detailed information about the fast regulatory mechanisms involved in arterial blood pressure (ABP) and renal blood flow (RBF) autoregulation.
P. Markova, R. Girchev
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Dose and Time-Dependent Effects of Caffeine on Cardiovascular Changes Induced by Adenosine
Brazilian Archives of Biology and Technology, 2023 Adenosine is an important regulator within the cardiovascular system and modulates various processes through four distinct G protein-coupled receptors (A1, A2A, A2B, and A3), causing hypotension and reduced renal blood flow, which contributes to ischemia
Lucas Braga Albino +3 more
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