Sepsis is associated with circulatory dysfunction contributing to disturbed blood flow and organ injury. Decreased organ perfusion in sepsis is attributed, in part, to the loss of vasoregulatory mechanisms.
Forough Jahandideh +6 more
doaj +1 more source
Sympathetic nerve-derived ATP regulates renal medullary vasa recta diameter via pericyte cells: a role for regulating medullary blood flow? [PDF]
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins.
Crawford, C. +4 more
core +2 more sources
Altered renal hemodynamics and impaired myogenic responses in the fawn-hooded rat [PDF]
The present study examined whether an abnormality in the myogenic response of renal arterioles that impairs autoregulation of renal blood flow (RBF) and glomerular capillary pressure (PGC) contributes to the development of ...
Dokkum, R.P.E. (Richard) van +4 more
core +2 more sources
Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]
Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Friedrich, N. +5 more
core +1 more source
Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney. [PDF]
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects.
Dunn, Kadeshia +3 more
core +1 more source
Measurement of Renal Blood Flow in the Rat
The radioactive microsphere technique is a simple method for measurement of RBF and intrarenal blood flow distribution in the rat that does not require surgical manipulation of the kidney or general anesthesia. The results are reproducible and compatible with other established techniques.
John M. Weller +3 more
openaire +3 more sources
Evaluation of renal function in dogs using pulsed Doppler ultrasonography
Background: In human medicine, efforts have been made to evaluate venous blood flow in the kidneys to diagnose renal disease and estimate renal function.
Takami Ito +3 more
doaj +1 more source
Perspectives on Renal Blood Flow Autoregulation
ConclusionThere is a continuing debate in regard to the relative contribution of TGF and myogenic mechanisms in the control autoregulation in the kidney. Much of the controversy, relating to the relative importance of each mechanism can possibly be explained simply by considering the species from which evidence is derived. Differences in autoregulatory
Robert O. Banks, David M. Pollock
openaire +3 more sources
Renal failure in experimental sepsis: role of Endothelin and the Toll-like receptor 4 [PDF]
Sepsis is the leading cause of renal failure in critically ill patients, but the pathogenesis of septic kidney dysfunction is poorly defined. The current paradigm states that hypoperfusion and excessive renal vasoconstriction results in renal ischemia.
Fenhammar, Johan
core +1 more source
Organs Blood Flow during Elevation of Body Temperature in Sevoflurane Anesthetized Rats
The aim of this study is to investigate how elevation of body temperature changes organs blood flow during sevoflurane anesthesia. We conducted in vivo research on 14 male Wistar rats to monitor pulse rate and arterial blood pressure and measure hepatic,
Koichi Shimo, Ko Takakura, Kenji Shigemi
doaj +1 more source

