Renal blood flow and oxygenation drive nephron progenitor differentiation.
During kidney development, the vasculature develops via both angiogenesis (branching from major vessels) and vasculogenesis (de novo vessel formation). The formation and perfusion of renal blood vessels are vastly understudied.
Christopher Rymer+10 more
semanticscholar +1 more source
Sepsis is associated with circulatory dysfunction contributing to disturbed blood flow and organ injury. Decreased organ perfusion in sepsis is attributed, in part, to the loss of vasoregulatory mechanisms.
Forough Jahandideh+6 more
doaj +1 more source
Phenotyping renal leukocyte subsets by four-color flow cytometry: Characterization of chemokine receptor expression [PDF]
To investigate mechanisms of cell-mediated injury in renal inflammatory disease it is critical to determine the surface phenotype of infiltrating renal leukocyte subsets.
Anders, Hans-Joachim+5 more
core +1 more source
Objective: We compared the effects of intravenous infusions of 0.9% saline ([Cl−] 154 mmol/L) and Plasma-Lyte 148 ([Cl−] 98 mmol/L, Baxter Healthcare) on renal blood flow velocity and perfusion in humans using magnetic resonance imaging (MRI). Background:
A. Chowdhury+3 more
semanticscholar +1 more source
Synchronized renal blood flow dynamics mapped with wavelet analysis of laser speckle flowmetry data. [PDF]
Full-field laser speckle microscopy provides real-time imaging of superficial blood flow rate. Here we apply continuous wavelet transform to time series of speckle-estimated blood flow from each pixel of the images to map synchronous patterns in ...
Alexey R Brazhe+3 more
doaj +1 more source
Extremely weakly-supervised blood vessel segmentation with physiologically based synthesis and domain adaptation [PDF]
Accurate analysis and modeling of renal functions require a precise segmentation of the renal blood vessels. Micro-CT scans provide image data at higher resolutions, making more small vessels near the renal cortex visible. Although deep-learning-based methods have shown state-of-the-art performance in automatic blood vessel segmentations, they require ...
arxiv
Ornipressin in the treatment of functional renal failure in decompensated liver cirrhosis [PDF]
In 11 patients with decompensated cirrhosis and deteriorating renal function, the effect of the vasoconstrictor substance 8-ornithin vasopressin (ornipressin; POR 8; Sandoz, Basel, Switzerland) on renal function, hemodynamic parameters, and humoral ...
Alexander L. Gerbes+66 more
core +1 more source
Altered renal hemodynamics and impaired myogenic responses in the fawn-hooded rat [PDF]
The present study examined whether an abnormality in the myogenic response of renal arterioles that impairs autoregulation of renal blood flow (RBF) and glomerular capillary pressure (PGC) contributes to the development of ...
Dokkum, R.P.E. (Richard) van+4 more
core +2 more sources
Role of renal sympathetic nerve activity in volatile anesthesia's effect on renal excretory function [PDF]
Regulation of fluid balance is pivotal during surgery and anesthesia and affects patient morbidity, mortality, and hospital length of stay. Retention of sodium and water is known to occur during surgery but the mechanisms are poorly defined.
DiBona, Gerald F+8 more
core +1 more source
Suprarenal aortic clamping and reperfusion decreases medullary and cortical blood flow by decreased endogenous renal nitric oxide and PGE2 synthesis [PDF]
ObjectiveThis study examined the hypothesis that clamping the aorta above the superior mesenteric artery (SMA) followed by suprarenal aortic clamping and reperfusion (SRACR) decreases microvascular blood flow by loss of endogenous medullary and cortical ...
Bartula, Lori L.+3 more
core +1 more source