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Renal cell carcinoma (RCC) denotes cancer originated from the renal epithelium and accounts for >90% of cancers in the kidney. The disease encompasses >10 histological and molecular subtypes, of which clear cell RCC (ccRCC) is most common and accounts for most cancer-related deaths. Although somatic VHL mutations have been described for some time, more-
Hsieh, James J.+8 more
semanticscholar +9 more sources
Clinicopathologic features of renal cell carcinomas seen at the Aga Khan University Hospital in Kenya [PDF]
Introduction: Kidney cancer accounted for 1. 8% of global cancer deaths according to Globocan 2020 estimates, with most of these being renal cell carcinomas. Lower rates of renal cell carcinoma are reported for Africa and these are expected to change for
Gakinya, Samuel, Mutuiri, Anderson
core +4 more sources
Renal Cell Carcinoma (RCC) has the highest mortality rate of the genitourinary cancers and the incidence of RCC has risen steadily. If detected early, RCC is curable by surgery although a minority are at risk of recurrence. Increasing incidental detection and an ageing population has led to active surveillance as an option for patients with small renal
openaire +6 more sources
Renal cell carcinoma remains a major challenge for urologic oncologists. Over the past year, progress has been made in understanding the molecular biology of this disease and in describing new prognostic factors for outcome following nephrectomy. Studies have better defined patients who might benefit from elective nephron-sparing procedures without ...
David M. Nanus+7 more
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Renal papillary carcinoma developed in a kidney transplant recipient with late IgA-nephropathy [PDF]
With improvements in immunosuppressive therapy, patient and graft survival in renal transplant recipients have been prolonged. Increasing donor age and patient survival rates have been related to an increase in the number of de novo tumors ...
BERLOCO, Pasquale Bartolomeo+7 more
core +1 more source
Radiogenomics in clear cell renal cell carcinoma: correlations between advanced CT imaging (texture analysis) and microRNAs expression [PDF]
Purpose: A relevant challenge for the improvement of clear cell renal cell carcinoma management could derive from the identification of novel molecular biomarkers that could greatly improve the diagnosis, prognosis, and treatment choice of these ...
Badia, S.+12 more
core +1 more source
Effects of phlebotomy on the growth of ferric nitrilotriacetate-induced renal cell carcinoma. [PDF]
The ferric nitrilotriacetate-induced carcinogenesis model is unique in that reactive oxygen species-free radicals are involved in the carcinogenic process.
Fujisawa, Masayoshi+5 more
core +1 more source
A novel combination of triple metachronous malignancies of the kidney, oropharynx and prostate. A case report [PDF]
Synchronous or metachronous malignancies are a rare event, with an incidence rate that increases with age. The present study reports the case of a 70-year-old Caucasian male who was referred to the outpatient office of the Urology Unit, Sapienza ...
Carbone, Antonio+6 more
core +1 more source
The treatment of renal cell carcinoma (RCC) has changed greatly over the past 15 years. Progress in the surgical management of the primary tumor and increased understanding of the molecular biology and genomics of the disease have led to the development of new therapeutic agents.
W. Kimryn Rathmell+2 more
openaire +3 more sources
Renal cell cancer (RCC) accounts for approximately 2–3 % of all human malignancies and shows a worldwide increase of incidence rate of 2 % per year [1]. It primarily affects men and women at the age of 50–70 years with a twofold higher incidence rate in men.
Börje Ljungberg+2 more
openaire +3 more sources