Results 131 to 140 of about 1,140,223 (331)

Human renal carcinoma cells produce hypercalcemia in the nude mouse and a novel protein recognized by parathyroid hormone receptors. [PDF]

, 1983
Gordon J Strewler, Richard D. Williams, Robert A. Nissenson   +2 more
openalex   +1 more source

Phosphorylation‐Dependent Stabilization of Collaborator of ARF (CARF) Suppresses Lymphoma Cell Proliferation

Advanced Science, EarlyView.
This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu, Zhuang Wei, Shuting Zhou, Xiaofan Zhang, Wenjun Zhang, Aibin Liang, Zhe Wang, Hongwei Xue   +7 more
wiley   +1 more source

Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

Nature Network Boston, 2020
D. Braun, Yue Hou, Z. Bakouny, M. Ficial, Miriam Sant’ Angelo, J. Forman, P. Ross-Macdonald, Ashton C. Berger, O. Jegede, L. Elagina, J. Steinharter, Maxine Sun, M. Wind-Rotolo, Jean-Christophe Pignon, A. Cherniack, Lee T Lichtenstein, D. Neuberg, P. Catalano, G. Freeman, A. Sharpe, D. McDermott, E. V. Van Allen, S. Signoretti, Catherine J. Wu, S. Shukla, T. Choueiri   +25 more
semanticscholar   +1 more source

Small renal cell carcinoma accompanied by extensive inferior vena cava tumor thrombus diagnosed by percutaneous transvenous biopsy

IJU Case Reports
Introduction Up to 10% of patients with renal cell carcinoma present with tumor thrombus in the inferior vena cava. We report that a case of small renal cell carcinoma with tumor thrombus extending above the diaphragm for which transvenous biopsy was ...
Hikaru Tsukada, Nozomi Hayakawa, Koichiro Aida, Shinji Wada, Tsuyoshi Morimoto, Masatomo Doi, Hidefumi Mimura, Junki Koike, Eiji Kikuchi   +8 more
doaj   +1 more source

A CASE OF RENAL CELL CARCINOMA MANIFESTED A TYPICAL NEPHROTIC SYNDROME

, 1964
Yasushi Ueda, Tadashi Miyahara, Sadao MINAMI, Tsukasa Saito, Yosuke Ogura   +4 more
openalex   +2 more sources

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In SETD2‐mutant ccRCC, the original LEDGF recognition of the H3K36me3 regulatory axis no longer exists. LEDGF interacts with CARM1‐dependent H3R17me2a regulating the transcription of key enzymes in the de novo synthesis pathway. The abnormally elevated LEDGF leads to the accumulation of purine nucleotides in SETD2‐mutant ccRCC, thereby satisfying the ...
Yuwei Zhang, Yuhua Zhou, Yuezhou Zhang, Jing Lv, Yang Shen, Dong Zhang, Bo Liu, Wei Zhao, Junyi Ju, Qingyi Zhu, Ke Wang, Ninghan Feng   +11 more
wiley   +1 more source

TRANSCATHETER EMBOLIZATION OF RENAL CELL CARCINOMA

, 1975
Harvey M. Goldstein, Héctor Medellín, M. TALAL BEYDOUN, Sidney Wallace, Yoram Ben‐Menachem, R. Bruce Bracken, Douglas E. Johnson   +6 more
openalex   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

MTCH2 Deficiency Promotes E2F4/TFRC‐Mediated Ferroptosis and Sensitizes Colorectal Cancer Liver Metastasis to Sorafenib

Advanced Science, EarlyView.
This study identifies MTCH2 as a crucial regulator of ferroptosis in colorectal cancer (CRC) progression. High expression of MTCH2 is correlated with poor prognosis in CRC patients. Furthermore, MTCH2 depletion induces ferroptosis to suppress CRC liver metastasis via the E2F4/TFRC axis and sensitizes tumors to sorafenib treatment, supporting MTCH2 as a
Pu Xing, Jiangbo Chen, Hao Hao, Xiaowen Qiao, Xinying Yang, Kai Weng, Jie Chen, Lin Song, Tianqi Liu, Yifan Hou, Tongkun Song, Yumeng Ran, Bo Chen, Hong Yang, Wei Zhao, Zaozao Wang, Jiabo Di, Beihai Jiang, Xiangqian Su   +18 more
wiley   +1 more source

Phase II study of high dose weekly intravenous human lymphoblastoid interferon in renal cell carcinoma [PDF]

, 1987
E. Eisenhauer, HK Silver, PM Venner, M. P. Thirlwell, Brian Weinerman, CML Coppin   +5 more
openalex   +1 more source