Microbubble Shell Stiffness Engineering Enhances Ultrasound Imaging, Drug Delivery, and Sonoporation
Advanced Materials, EarlyView.Shell‐engineered poly(alkyl cyanoacrylate) microbubbles with tunable stiffness improve ultrasound imaging and therapy. Adjusting the length of the alkyl chain and the glass transition temperature maintains a narrow microbubble size distribution while enhancing drug loading, sonoporation and the acoustic response.
Roman A. Barmin +30 more
wiley +1 more source
Frontiers in PharmacologyIntroductionThe pathogenesis of renal fibrosis is related to blood stasis, and the method of promoting blood circulation and removing blood stasis is often used as the treatment principle.
Yiwen Cao +13 more
doaj +1 more source
Nephropathia epidemica and Puumala virus occurrence in relation to bank vole (Clethrionomys glareolus) dynamics and environmental factors in northern Sweden [PDF]
, 2003 The objectives of the thesis were to investigate the spatio-temporal patterns of nephropathia epidemica (NE) in humans and Puumala virus (PUU) occurrence in relation to bank vole (Clethrionomys glareolus) dynamics and environmental factors in a region of
Olsson, Gert E.
core
Function of connexins in the renal circulation [PDF]
Kidney International, 2008 Connexins form intercellular channels that span two plasma membranes and directly couple the cytoplasm of adjacent cells. This morphological contact enables the exchange of ions, second messengers, and metabolites, which act to regulate several biological functions. This review focuses on the significance of connexins in the renal circulation. Cells of
openaire +2 more sources
Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications
Advanced Materials, EarlyView.Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi +7 more
wiley +1 more source
, 2012 This study describes the distribution of intravenously injected polyacrylic acid (PAA) coated {\gamma}-Fe2O3 NPs (10 mg kg-1) at the organ, cellular and subcellular levels in healthy BALB/cJ mice and in parallel addresses the effects of NP injection on ...
Baatrup, Erik +10 more
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Improving Postdischarge Outcomes in Acute Heart Failure [PDF]
, 2018 The global burden that acute heart failure (AHF) carries has remained unchanged over the past several decades (1). European registries (2–5) showed that 1-year outcome rates remain unacceptably high (Table 1) and confirm that hospitalization for AHF ...
Ambrosy, Andrew P. +8 more
core +1 more source
Advanced Materials, EarlyView.An acid‐responsive polymeric micelle system based of aliphatic poly(carbonate)s with benzyl ketal side chains is designed for targeted immunodrug delivery. It can disassemble in endosomal environments, enabling site‐specific immunoactivation and enhanced biodegradability.
Adrian V. Hauck +16 more
wiley +1 more source
Effect of a reduction in glomerular filtration rate after nephrectomy on arterial stiffness and central hemodynamics: rationale and design of the EARNEST study [PDF]
, 2014 Background: There is strong evidence of an association between chronic kidney disease (CKD) and cardiovascular disease. To date, however, proof that a reduction in glomerular filtration rate (GFR) is a causative factor in cardiovascular disease is ...
Alam +73 more
core +2 more sources
Oxygen delivery during cardiopulmonary bypass (and renal outcome) using two systems of extracorporeal circulation: a retrospective review [PDF]
, 2013 Mark J. Bennett +5 more
openalex +1 more source