Results 131 to 140 of about 2,167,615 (375)

Takayasu's arteritis in children : a review [PDF]

, 2001
Takayasu's arteritis is an inflammatory disease of unknown origin involving aorta, its primary branches and pulmonary artery. This article briefly reviews the pathology, clinical features and treatment of Takayasu's arteritis, focusing mainly on the ...
Kothari, Shyam S.
core   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

Temporary Balloon Occlusion of the Common Hepatic Artery for Yttrium-90 Glass Microspheres Administration in a Patient with Hepatocellular Cancer and Renal Insufficiency

Case Reports in Radiology, 2013
The most severe complication of yttrium-90 therapy is gastrointestinal ulceration caused by extrahepatic dispersion of microspheres. Standard pretreatment planning requires extensive angiographic evaluation of the hepatic circulation and embolization of ...
Justin Smith, Ravi Murthy, Amit Lahoti, Bruno Odisio, Rony Avritscher, Beth Chasen, Armeen Mahvash   +6 more
doaj   +1 more source

Relationship between aortic valve stenosis and the hemodynamic pattern in the renal circulation, and restoration of the flow wave profile after correction of the valvular defect. [PDF]

J Int Med Res, 2020
Bardelli M, Cavressi M, Furlanis G, Pinamonti B, Leone M, Albani S, Korcova R, Fabris B, Sinagra G.   +8 more
europepmc   +1 more source

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun, Elizabeth S. Nakasone, Ha Eun Shin, Hyojin Lee, Jong‐Chan Park, Wonhwa Lee, Wooram Park, Chun Gwon Park, Juwon Park, Se‐Na Kim   +9 more
wiley   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Diagnostic and prognostic value of Doppler ultrasound study in hepatorenal syndrome. A report of a case

Acta Médica del Centro, 2016
Hepatorenal syndrome is a condition that occurs in patients with chronic liver disease characterized by portal hypertension and it is distinguished by the deterioration of renal function and marked abnormalities in blood circulation, with activation of ...
Raysa Garay Padrón, Milagros Hernández Fernández, Arai Peña Bernal   +2 more
doaj  

The role of nitric oxide in nephroprotection during surgical correction of congenital heart disease in children (literature review)

Вестник анестезиологии и реаниматологии
Introduction. The need to develop effective methods of renal protection during cardiac surgical interventions is dictated by the progressive increase of acute kidney injury (CS-AKI) in children, which is associated with immaturity of renal function and ...
P. V. Zinchuk, A. A. Ivkin, E. V. Grigoriev, D. G. Balakhnin   +3 more
doaj   +1 more source

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Advanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai, Xinyue Lao, Sin‐Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao   +6 more
wiley   +1 more source

Metabolism and secretion of retinol transport complex in acute renal failure

Journal of Lipid Research, 1991
Tissue uptake and distribution of retinol from circulatory vitamin A transport complex was studied in order to determine the origin of the increased serum retinol in rats with short-term acute renal failure.
TH Gerlach, MH Zile
doaj