Results 201 to 210 of about 2,140,639 (395)
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri+10 more
wiley +1 more source
Abstract Background Antibody–drug conjugates (ADCs) have complex molecular structures and have been tested in numerous clinical trials. Therefore, understanding the mechanisms of their toxicity when applied in medical practice is of high importance. Methods In a systematic review and meta‐analysis of data gathered from different scientific databases ...
Youwen Zhu+3 more
wiley +1 more source
STUDIES ON THE EFFECTS OF WATER, PAH, GLUCOSE AND SEVERAL DRUGS ON RENAL CIRCULATION AND METABOLISM
Takao Ikeda
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Maternal obesity and resistance to breast cancer treatments among offspring: Link to gut dysbiosis
Abstract Background About 50 000 new cases of cancer in the United States are attributed to obesity. The adverse effects of obesity on breast cancer may be most profound when affecting the early development; that is, in the womb of a pregnant obese mother.
Fabia de Oliveira Andrade+2 more
wiley +1 more source
beta‐Adrenoceptor‐blocking agents and the kidney: effect of nadolol and propranolol on the renal circulation. [PDF]
Hollenberg Nk+5 more
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Hematoxylin–eosin (H&E) stains of the heart, liver, lung, and kidney show acute toxicity. Abstract Background To investigate the toxicity of N‐n‐butyl haloperidol iodide (F2), a quaternary ammonium salt derivative of haloperidol, in mice for potential therapeutic purposes. Methods The acute median lethal dose (LD50) of F2 was determined using the Bliss
Jilin Liao+6 more
wiley +1 more source
Pharmacological contributions on diuresis and the renal circulation
中澤 與四郎, 上野 昭, 酒井 潔
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Application of humanized mice in the safety experiments of antibody drugs
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun+9 more
wiley +1 more source
Hypertension as a Presentation of Bilateral Intrarenal Arateriovenous Malformation
Congenital arteriovenous malformations are rare lesions of the kidneys. The first case of bilateral renal arteriovenous malformations was described in 1987.
El-Lozi Mohamed, Hadad A
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