Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
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Large animal models for the assessment of snakebite envenoming therapies. [PDF]
Benard-Valle M +7 more
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Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr +9 more
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Serological profiling of hantavirus infections in chronic kidney disease of unknown etiology non-endemic regions of Sri Lanka. [PDF]
Senarathne P +10 more
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Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen +14 more
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Controlled patient blood management under visceral perfusion in open treatment of complex aortic pathologies. [PDF]
Rusch M, Hoffmann G, Alasad N, Rusch R.
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Peri-implantitis: a systemic burden for our patients. [PDF]
Cafferata EA, Schwarz F.
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Abstract To solidify their power over society, totalitarian regimes will usually eliminate any dissent, any perceived threats early on. These threats include not only political enemies but also educated and independent segments of society, such as professional associations.
Michael Hortsch
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Investigating a modified Yiqi Huoxue formula for chronic glomerulonephritis: Effects on clinical efficacy, renal function, and inflammation. [PDF]
Liu X, Sun J.
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Abstract As habitat salinity markedly differs between the endangered, freshwater‐dwelling Saimaa ringed seal (Pusa saimensis Nordquist, 1899) and the brackish water‐inhabiting Baltic ringed seal (Pusa hispida botnica Gmelin, 1788), we investigated whether this difference has resulted in morphological changes to their kidneys.
Heini Nihtilä, Juha Laakkonen
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