Results 241 to 250 of about 392,678 (306)

TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays

open access: yesArthritis &Rheumatology, EarlyView.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu   +12 more
wiley   +1 more source

Targeting gut-liver-kidney axis: microbiota-derived metabolites and therapeutic implications. [PDF]

open access: yesCell Commun Signal
Zhang Y   +6 more
europepmc   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

open access: yesArthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó   +84 more
wiley   +1 more source

Bacterial Extracellular Vesicles Mediate Microbiota-Host Communication to Regulate Blood Pressure in Male Rats. [PDF]

open access: yesHypertension
Shi H   +8 more
europepmc   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

open access: yesArthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki   +8 more
wiley   +1 more source

Albumin-Keratin Casts Obstruct Renal Tubular and Vascular Lumens Following Kidney Ischemia. [PDF]

open access: yesKidney Int Rep
Bryant M   +16 more
europepmc   +1 more source

Mesenteric Steal Syndrome Caused by Abdominal Aortic Stenosis due to Takayasu Arteritis. [PDF]

open access: yesSurg Case Rep
Nagashima S   +7 more
europepmc   +1 more source

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