Results 261 to 270 of about 2,205,306 (373)
PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley +1 more source
Perspective: Vitamin D Deficiency Relationship to Initiation of Diseases. [PDF]
Fraser DR.
europepmc +1 more source
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu +15 more
wiley +1 more source
Management of earthquake-related acute renal injury. [PDF]
Abu-Zidan FM, Idris K, Cevik AA.
europepmc +1 more source
Mechanotransduction in Shaping Immunity: Pathways, Crosstalk, and Pathophysiological Relevance
This review comprehensively summarizes the role of mechanotransduction in shaping immunity. It details how immune cells respond to biomechanical cues via mechanotransduction cascades and emphasizes the mechanical crosstalks within the immune microenvironment. The emerging significance of mechanoimmunology in both health and diseases is also highlighted.
Ruijiao Yan +7 more
wiley +1 more source
Benefits and challenges to therapeutic targeting of bile acid circulation in cholestatic liver disease. [PDF]
Trauner M, Karpen SJ, Dawson PA.
europepmc +1 more source
Cysteine‐tagged silk‐elastin‐like proteins, a family of tri‐block chimeric proteins that consist of a photothermal agent binding motif, silk motif, and elastin motif is developed to form a responsive in situ hydrogel for late‐stage and metastatic triple‐negative breast cancer.
Xinchen Shen +11 more
wiley +1 more source

